Prochlorperazine vs Imitrex for Acute Migraine in the Emergency Department
Information source: United States Naval Medical Center, Portsmouth
Information obtained from ClinicalTrials.gov on June 20, 2008
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Acute Migraine Headache
Intervention: prochlorperazine and benadryl IV (Drug); Imitrex SubQ, saline IV (Drug)
Phase: N/A
Status: Completed
Sponsored by: United States Naval Medical Center, Portsmouth Official(s) and/or principal investigator(s):
Frank Gutierrez, MD, Principal Investigator, Affiliation: US Navy
Summary
ED patients with acute migraine will be randomized to either prochlorperazine and Bendaryl OR
imitrex. VAS for pain will be monitored, along with side effects. Primary outcome measure is
improvement in pain scales between the groups.
Clinical Details
Official title: Prochlorperazine vs Imitrex for Acute Migraine in the Emergency Department
Study design: Treatment, Randomized, Double Blind (Subject, Investigator), Active Control, Parallel Assignment, Safety/Efficacy Study
Primary outcome: Difference in pain measured by VAS
Secondary outcome: Degree of sedation, nausea, akathisia
Eligibility
Minimum age: 18 Years.
Maximum age: 50 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Acute migraine headache
Exclusion Criteria:
- Pregnant
- Hypertension
- Chest pain
- < 18
- Allergy to any of the meds
Locations and Contacts
Naval Medical Center Portsmouth, Portsmouth, Virginia 23708, United States
Additional Information
Starting date: February 2007
Ending date: May 2007
Last updated: December 13, 2007
|
