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Study Evaluating Piperacillin-Tazobactam on Certain Bacteria in Hematology and Oncology Units

Information source: Wyeth is now a wholly owned subsidiary of Pfizer
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Gram-Positive Bacterial Infections; Escherichia Coli Infections; Klebsiella Infections

Intervention: piperacillin-tazobactam (Drug)

Phase: Phase 4

Status: Completed

Sponsored by: Wyeth is now a wholly owned subsidiary of Pfizer

Official(s) and/or principal investigator(s):
Medical Monitor, Study Director, Affiliation: Wyeth is now a wholly owned subsidiary of Pfizer


To determine the value of increasing use of piperacillin/tazobactam as empiric therapy and restricting extended-spectrum cephalosporins in reducing the cases of ESBL producing Escherichia coli and Klebsiella pneumoniae in hematology and oncology units

Clinical Details

Official title: Effects of Piperacillin-Tazobactam Use on the Prevalence Rate of Extended-Spectrum Beta-Lactamase (ESBL) Producing Escherichia Coli and Klebsiella Pneumoniae in Hematology and Oncology Units.

Study design: Observational Model: Case Control, Time Perspective: Longitudinal


Minimum age: 15 Years. Maximum age: N/A. Gender(s): Both.


Inclusion Criteria:

- Eligible patients of either sex, 15 years of age or older

- Patients who are admitted to the department of hematology and oncology

- Provide written informed consent

Exclusion Criteria:

- Patients who have hypersensitivity to β-lactam antibiotics

- Female who are pregnant or breast-feeding

- Any underlying conditions or non-infectious diseases that will be ultimately fatal

within 30 days

Locations and Contacts

Seoul 133-792, Korea, Republic of
Additional Information

Starting date: February 2005
Last updated: March 14, 2007

Page last updated: August 23, 2015

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