Patients with symptomatic idiopathic (IPAH) or familial (FPAH) pulmonary arterial
hypertension in New York Heart Association (NYHA) class II to IV , naive to PAH treatment or
currently being treated with a stable dose of either bosentan or sildenafil and who complete
PROWESS 15 will be enrolled in the PROWESS 15 Extension study. This is a double-blind (12
week), randomized study to compare the safety and tolerability of inhaled iloprost power
disc-15 and power disc-6 in patients with symptomatic pulmonary arterial hypertension (PAH).
After completion of the double blind period, patients will be entered in the open label
period using iloprost power disc-15.
Minimum age: 18 Years.
Maximum age: N/A.
Gender(s): Both.
LHK Universitatsklinikum Graz, Graz 8036, Austria
Universitatsklinikum Carl-Gustav-Carus, Dresden D-01307, Germany
UCSD Medical Center, La Jolla, California 92037, United States
UC Davis Medical Center, Sacramento, California 95817, United States
Liu Center for Pulmonary Hypertension - LA Biomedical Research Institute at Harbor-UCLA, Torrance, California 90502, United States
Lung Health & Sleep Enhancement Center, LLC, Newark, Delaware 19713, United States
University of Florida, Gainesville, Florida 32610, United States
Pulmonary & Critical Care of Atlanta, Atlanta, Georgia 30342, United States
Atlanta Institute for Medical Research, Decatur, Georgia 30033, United States
Mercy Hospital, Iowa City, Iowa 52245, United States
University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, United States
Kentuckiana Pulmonary Associates, Louisville, Kentucky 40202, United States
LSU Health Sciences Center, New Orleans, Louisiana 70112, United States
University of Maryland Medical Center, Baltimore, Maryland 21201, United States
University of Nebraska Medical Center, Omaha, Nebraska 68198, United States
Newark Beth Israel Medical Center, Newark, New Jersey 07112, United States
Winthrop University Hospital, Mineola, New York 11501, United States
University of North Carolina, Chapel Hill, North Carolina 27599-7020, United States
The Lindner Clinical Trial Center, Cincinnati, Ohio 45219, United States
The Ohio State University Medical Center, Columbus, Ohio 43221, United States
Legacy Health System, Portland, Oregon 97210, United States
Temple University Hospital, Philadelphia, Pennsylvania 19140, United States
Allegheny General Hospital, Pittsburgh, Pennsylvania 15212, United States
Rhode Island Hospital, Providence, Rhode Island 02903, United States
Lexington Pulmonary & Critical Care, Lexington, South Carolina 29072, United States
UT Southwestern Medical Center Heart Lung and Vacular Center, Dallas, Texas 75390-8550, United States
University of Texas Medical School, Houston, Texas 77030, United States
Central Utah Clinic, P.C., American Fork, Utah 84003, United States
Intermountain Medical Center, Murray, Utah 84157, United States
University of Virginia, Charlottesville, Virginia 22908, United States
Sentara Hospitals T/A Sentara Cardiovascular Research Institute, Norfolk, Virginia 23507, United States
Spokane Respiratory Consultants, Spokane, Washington 99204, United States
UW Hospital & Clinics, Madison, Wisconsin 53792, United States
Comprehensive Cardiovascular Care LLP, Milwaukee, Wisconsin 53215, United States