Effect of Growth Hormone on Insulin Signaling in Muscle Tissue
Information source: University of Aarhus
Information obtained from ClinicalTrials.gov on June 20, 2008
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Insulin Resistance
Intervention: Physiological Bolus of Growth Hormone (Device)
Phase: N/A
Status: Active, not recruiting
Sponsored by: University of Aarhus Official(s) and/or principal investigator(s):
Jens Otto L Jørgensen, MD, DMSc, Principal Investigator, Affiliation: Department M (endocrinology and diabetes), Aarhus University Hospital, Norrebrogade 44, 8000 Aarhus C, Denmark
Summary
The purpose of this study is to examine the effects of a physiological bolus of growth
hormone on insulin signaling pathways in muscle tissue in healthy lean men.
Clinical Details
Official title: The Effect of a Physiological Bolus of Growth Hormone (GH) on Insulin Signaling Pathways in Muscle Tissue From Healthy Adults
Study design: Basic Science, Randomized, Single Blind (Subject), Placebo Control, Factorial Assignment
Primary outcome: PI3-kinase activity i muscle tissue
Secondary outcome: Growth Hormone Signaling Proteins in Muscle Tissue and other Insulin Signaling Proteins in Muscle Tissue
Eligibility
Minimum age: 18 Years.
Maximum age: 30 Years.
Gender(s): Male.
Criteria:
Inclusion Criteria:
- Male
- Healthy
- Age between 18 and 30 years
- BMI ≤ 26
Exclusion Criteria:
- Known present disease including diabetes mellitus
- BMI > 26
- Uses any medication
- Consumes > 21 units of alcohol per week
Locations and Contacts
Department M (endocrinology and diabetes), Aarhus 8000, Denmark
Additional Information
Starting date: May 2007
Ending date: August 2008
Last updated: February 21, 2008
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