The Feasibility of Different Doses of Etomidate Admixed With Propofol in Induced Abortion: A Randomized, Double Blind Controlled Trial
Information source: Third Affiliated Hospital of Zhengzhou University
ClinicalTrials.gov processed this data on August 23, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Induced Abortion; Anesthesia
Intervention: pentazocine (Drug); propofol (Drug); Etomidate (Drug)
Phase: Phase 4
Status: Not yet recruiting
Sponsored by: Third Affiliated Hospital of Zhengzhou University
Summary
To explore the feasibility of different doses of etomidate admixed with propofol in induced
abortion: a randomized, double blind controlled trial.
Clinical Details
Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
Primary outcome: Heart rateBlood pressure Pulse oxygen saturation
Secondary outcome: Efficacy of anesthesiaDose of propofol or mixture of propofol and etomidate Use of specific medications Aldrete score Verbal rating scales of uterine contraction Satisfaction degree of the patient, the surgeon and the anesthetist
Eligibility
Minimum age: 20 Years.
Maximum age: 35 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Aged between 20 and 35 years
- American Society of Anesthesiology (ASA) Physical Status: Ⅰ or Ⅱ
- Singleton pregnancy and the gestational period is 6 to 8 weeks
- Expected operation duration is within 60 minutes
- The body weight should be within 15% around the standard weight
- Signed informed consent form
Exclusion Criteria:
- Serious cardiac, cerebral, liver, kidney, lung, endocrine disease
- Upper respiratory infections within 4 weeks
- Long use of hormone or history of adrenal suppression
- History of use of glucocorticoids, aprotinin or immunosuppressant
- Manifestation of immunodeficiency
- History of use of sedatives or opiates
- Needs of Neuromuscular blocker (except intubation)
- Allergy to trial drug or other contraindication
- Pregnant or breast-feeding women
- Attended other trial past 30 days
Locations and Contacts
Additional Information
Starting date: September 2014
Last updated: August 3, 2014
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