Intraocular Pressure Reduction With the Bimatoprost/Timolol Fixed Combination
Information source: Larissa University Hospital
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Glaucoma; Ocular Hypertension
Intervention: Bimatoprost and Bimatoprost/Timolol fixed combination. (Drug)
Phase: Phase 4
Status: Completed
Sponsored by: Larissa University Hospital
Summary
The purpose of this study is to examine the ocular hypotensive effect of Bimatoprost and the
potential additional effect of the Bimatoprost/Timolol fixed combination in eyes with ocular
hypertension, primary open angle glaucoma or exfoliation glaucoma.
Clinical Details
Official title: Efficacy Of The Bimatoprost/Timolol Fixed Combination In Patients Treated With Bimatoprost for Primary Open Angle Glaucoma, Exfoliation Glaucoma or Ocular Hypertension.
Study design: Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
Primary outcome: Mean diurnal intraocular pressure
Eligibility
Minimum age: 18 Years.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Primary open angle glaucoma
- Exfoliation glaucoma
- Ocular hypertension
Exclusion Criteria:
- Younger than 18 years old
- Inability to understand and/or follow study requirements
- Women of childbearing potential not using reliable birth control, pregnant or
lactating women
- History of chronic obstructive pulmonary disease, heart failure, 2nd or 3rd AV block
- Anticipated modification of treatment for systemic hypertension during the study
period
- History of ocular herpes, corneal scarring, conventional or laser surgery or macular
pathology
- History of allergy, poor tolerability or poor response to study medication
- Best corrected visual acuity less than 0. 4
- Significant visual field defect (MD<15. 0 dB)
Locations and Contacts
University Eye Clinic, Larissa, Thessaly 41110, Greece
Additional Information
Starting date: July 2009
Last updated: November 29, 2010
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