Buprenorphine and Methadone for Opioid Dependent Chronic Pain Patients
Information source: State University of New York at Buffalo
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Opiate Addiction
Intervention: Methadone (Drug); Buprenorphine/naloxone (Drug)
Phase: Phase 4
Status: Completed
Sponsored by: State University of New York at Buffalo Official(s) and/or principal investigator(s):
Richard D Blondell, MD, Principal Investigator, Affiliation: SUNY Buffalo
Summary
The purpose of this study is to determine if buprenorphine or methadone is better for the
treatment of chronic pain among patients who have become addicted to prescription narcotics.
Clinical Details
Official title: A Randomized Controlled Trial Comparing Buprenorphine and Methadone for Opioid Dependent Chronic Pain Patients
Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Primary outcome: Number of Participants Retained in Treatment
Secondary outcome: Numerical Rating Score for PainNumerical Rating Score for Functioning Self-reported Illicit Opioid Use
Detailed description:
The purpose of this randomized clinical trial is to compare methadone with buprenorphine for
the treatment of chronic pain among patients who have developed a physical dependence on
prescription opiate analgesics that is associated with psychosocial dysfunction (i. e.,
addiction).
Eligibility
Minimum age: 18 Years.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- chronic back pain
- opioid addiction
- not successful with abstinence
- at least 18 years old
- able to understand spoken English
- live in Western New York State (Erie or Niagara county)
- have health insurance or ability to pay for health care
- no methadone or buprenorphine treatment within past year
- not member of a vulnerable population (e. g., pregnancy, prisoner)
Exclusion Criteria:
- homelessness
- unable to give consent (e. g., dementia, psychosis)
- serious heart or lung disease
- taking a medication that could interact with methadone or buprenorphine
- pregnancy
Locations and Contacts
Erie County Medical Center, Buffalo, New York 14215, United States
Sheehan Memorial Hospital, Buffalo, New York 14203, United States
Additional Information
Starting date: April 2009
Last updated: August 3, 2012
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