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The Norepinephrine Transporter: A Novel Target for Imaging Brown Adipose Tissue

Information source: Yale University
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Brown Adipose Tissue

Intervention: PET imaging (Radiation)

Phase: Phase 0

Status: Completed

Sponsored by: Yale University

Official(s) and/or principal investigator(s):
Robert Sherwin, MD, Principal Investigator, Affiliation: Yale University


This study seeks to assess a novel imaging technique to image brown adipose tissue utilizing the norepinephrine transporter.

Clinical Details

Official title: The Norepinephrine Transporter: A Novel Target for Imaging Brown Adipose Tissue

Study design: Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Primary outcome: detection of brown adipose tissue based on PET imaging


Minimum age: 18 Years. Maximum age: 30 Years. Gender(s): Both.


Inclusion Criteria:

- age 18-30 yrs

- BMI < 24 kg/m2

- Caucasian

Exclusion Criteria:

- Current neuro-psychiatric illness

- substance abuse

- medical or neurological illnesses likely to affect physiology or anatomy, i. e.,

uncontrolled hypertension, cardiovascular disorders

- current pregnancy

- current breast feeding

- suicidal ideation or behavior

- use of medications which potentially affect NET binding within 2 weeks of the PET


Locations and Contacts

Yale University, New haven, Connecticut 06510, United States
Additional Information

Starting date: September 2012
Last updated: July 16, 2015

Page last updated: August 23, 2015

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