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Bioavailability of Potassium From Potatoes and Potassium Gluconate

Information source: Purdue University
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Potassium Bioavailability; Blood Pressure

Intervention: Placebo control (Dietary Supplement); Low dose potassium gluconate (Dietary Supplement); Medium dose potassium gluconate (Dietary Supplement); High dose potassium gluconate (Dietary Supplement); Low dose potato (Dietary Supplement); Medium dose potato (Dietary Supplement); High dose potato (Dietary Supplement); High dose French fries (Dietary Supplement); Basal diet control (Dietary Supplement)

Phase: N/A

Status: Recruiting

Sponsored by: Purdue University

Official(s) and/or principal investigator(s):
Connie M Weaver, Ph.D., Principal Investigator, Affiliation: Purdue University
Berdine R Martin, Ph.D., Study Director, Affiliation: Purdue University

Overall contact:
Berdine R Martin, Ph.D., Phone: 765-494-6559, Email: bmartin1@purdue.edu

Summary

This study is designed to compare the effect of sources of potassium on uptake and the effect of potassium on blood pressure.

Clinical Details

Official title: Bioavailability of Potassium From Potatoes and Potassium Gluconate

Study design: Allocation: Randomized, Endpoint Classification: Bio-availability Study, Intervention Model: Crossover Assignment, Masking: Single Blind (Subject)

Primary outcome: Bioavailability of Potassium

Secondary outcome: Blood Pressure Response to Potassium

Detailed description: The study will compare uptake of potassium from three different doses and sources; supplements (720, 1440 and 2160 mg) potatoes (720, 1440 and 2160 mg) or French fries (2160 mg). During 9 phases, participants will consume a controlled diet with the supplements, potato or french fries (every other week for 5 days). On the 4th day, blood and urine samples will be taken to monitor potassium uptake and excretion. Measures of blood pressure will be analyzed at defined time points throughout the intervention.

Eligibility

Minimum age: 20 Years. Maximum age: 60 Years. Gender(s): Both.

Criteria:

Inclusion Criteria:

- Able to adhere to the visit schedule, protocol requirements and available to

complete the study

- Normotensive men and women

- Aged 20-60 years

- BMI of 15-35

Exclusion Criteria:

- Medication to treat hypertension or hypotension

- Medication known to affect electrolyte metabolism or contain high levels of potassium

or sodium

- smoke cigarettes or use illegal drugs

- Hypertension or hypotension

- Diseases known to affect potassium metabolism

- Pregnant

- Allergic to nuts

Locations and Contacts

Berdine R Martin, Ph.D., Phone: 765-494-6559, Email: bmartin1@purdue.edu

Purdue University, West Lafayette, Indiana 47907, United States; Recruiting
Berdine R Martin, Ph.D., Phone: 765-494-6559, Email: bmartin1@purdue.edu
Additional Information

Starting date: March 2013
Last updated: June 17, 2013

Page last updated: August 23, 2015

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