Bioavailability of Potassium From Potatoes and Potassium Gluconate
Information source: Purdue University
ClinicalTrials.gov processed this data on August 23, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Potassium Bioavailability; Blood Pressure
Intervention: Placebo control (Dietary Supplement); Low dose potassium gluconate (Dietary Supplement); Medium dose potassium gluconate (Dietary Supplement); High dose potassium gluconate (Dietary Supplement); Low dose potato (Dietary Supplement); Medium dose potato (Dietary Supplement); High dose potato (Dietary Supplement); High dose French fries (Dietary Supplement); Basal diet control (Dietary Supplement)
Phase: N/A
Status: Recruiting
Sponsored by: Purdue University Official(s) and/or principal investigator(s): Connie M Weaver, Ph.D., Principal Investigator, Affiliation: Purdue University Berdine R Martin, Ph.D., Study Director, Affiliation: Purdue University
Overall contact: Berdine R Martin, Ph.D., Phone: 765-494-6559, Email: bmartin1@purdue.edu
Summary
This study is designed to compare the effect of sources of potassium on uptake and the
effect of potassium on blood pressure.
Clinical Details
Official title: Bioavailability of Potassium From Potatoes and Potassium Gluconate
Study design: Allocation: Randomized, Endpoint Classification: Bio-availability Study, Intervention Model: Crossover Assignment, Masking: Single Blind (Subject)
Primary outcome: Bioavailability of Potassium
Secondary outcome: Blood Pressure Response to Potassium
Detailed description:
The study will compare uptake of potassium from three different doses and sources;
supplements (720, 1440 and 2160 mg) potatoes (720, 1440 and 2160 mg) or French fries (2160
mg).
During 9 phases, participants will consume a controlled diet with the supplements, potato or
french fries (every other week for 5 days). On the 4th day, blood and urine samples will be
taken to monitor potassium uptake and excretion. Measures of blood pressure will be
analyzed at defined time points throughout the intervention.
Eligibility
Minimum age: 20 Years.
Maximum age: 60 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Able to adhere to the visit schedule, protocol requirements and available to
complete the study
- Normotensive men and women
- Aged 20-60 years
- BMI of 15-35
Exclusion Criteria:
- Medication to treat hypertension or hypotension
- Medication known to affect electrolyte metabolism or contain high levels of potassium
or sodium
- smoke cigarettes or use illegal drugs
- Hypertension or hypotension
- Diseases known to affect potassium metabolism
- Pregnant
- Allergic to nuts
Locations and Contacts
Berdine R Martin, Ph.D., Phone: 765-494-6559, Email: bmartin1@purdue.edu
Purdue University, West Lafayette, Indiana 47907, United States; Recruiting Berdine R Martin, Ph.D., Phone: 765-494-6559, Email: bmartin1@purdue.edu
Additional Information
Starting date: March 2013
Last updated: June 17, 2013
|