Effects of Naproxen on Physical Performance

Condition(s) targeted: Healthy

Intervention: Naproxen (Drug)

Phase: Phase 4

Status: Terminated

Sponsored by: University of Oklahoma

Official(s) and/or principal investigator(s):
LaMont Cavanagh, MD, Principal Investigator, Affiliation: University of Oklahoma-Tulsa

The purpose of this study is to determine the effect of daily use of Naproxen (a commonly used over-the-counter NSAID) on the physical performance of athletes, as measured by maximum oxygen consumption.

Official title: Effects of Naproxen on Physical Performance

Study design: Treatment, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment, Efficacy Study

Primary outcome: Effects on physical performance in terms of maximum oxygen consumption

Minimum age: 18 Years. Maximum age: 30 Years. Gender(s): Both.

Criteria:

Inclusion Criteria:

1. Age equal to or greater than18 years of age

2. No history of allergy or adverse reaction to any NSAID

3. No use of any NSAID in past 2 weeks

4. No history of peptic ulcer disease (PUD), gastroesophageal disease (GERD), or gastritis

5. No major medical history including but not limited to diabetes, hypertension, asthma, kidney disease and coronary artery disease

6. Currently not taking any medication including oral contraceptives

Exclusion Criteria:

1. Age < 18 years of age

2. History of allergy or adverse reaction to any NSAID

3. Use of any NSAID in past 2 weeks

4. History of a bleeding disorder

5. History of PUD, GERD, or gastritis

6. Pregnant

7. A medical history of diabetes, hypertension, asthma, kidney disease or coronary artery disease

8. Taking any medication including oral contraceptives

Family Practice - CMT, Tulsa, Oklahoma 74104, United States

Starting date: May 2004
Ending date: August 2006
Last updated: October 10, 2007