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Changes in Adrenal Hormones During Adrenal Radiofrequency Ablation

Information source: Mie University
Information obtained from ClinicalTrials.gov on October 04, 2010
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Adrenal Tumors

Intervention: RFA (Procedure)

Phase: N/A

Status: Recruiting

Sponsored by: Mie University

Official(s) and/or principal investigator(s):
Koichiro Yamakado, MD, Study Chair, Affiliation: Mie University School of Medicine

Overall contact:
Koichiro Yamakado, MD, Phone: +81-59-231-5029, Ext: 5630, Email: yama@clin.medic.mie-u.ac.jp

Summary

The purpose of this study is to evaluate changes in adrenal hormones during adrenal radiofrequency ablation.

Clinical Details

Official title: Changes in Adrenal Hormones During Adrenal Radiofrequency Ablation

Study design: Observational Model: Case-Only, Time Perspective: Prospective

Primary outcome: Increase in catecholamine

Secondary outcome: Increase in cortisol

Detailed description: Adrenal radiofrequency (RF) ablation has been increasingly used for the treatment of unresectable adrenal tumors. But one of the major complication is a increase in blood pressure. Hormonal release during RF ablation is considered the cause of hypertension. But there has been no evidence that adrenal hormones affects changes in blood pressure. In this prospective study, we evaluate the changes in adrenal hormones during RF ablation and clarify the cause of hypertensive crisis.

Eligibility

Minimum age: 20 Years. Maximum age: N/A. Gender(s): Both.

Criteria:

Inclusion Criteria:

- Unresectable adrenal tumor which will be treated by RF ablation

- Non-functioning tumor

- Blood pressure is 140mmHg or less before RF ablation

- Age of 20-years or more

- PS of 0 or 1

- Agreement from the patient

Exclusion Criteria:

- Platelet count of 50,000/mm3 or INR>1. 5

Locations and Contacts

Koichiro Yamakado, MD, Phone: +81-59-231-5029, Ext: 5630, Email: yama@clin.medic.mie-u.ac.jp

Mie University Hospital, Tsu, Mie 514-8507, Japan; Recruiting
Koichiro Yamakado, MD, Phone: +81-59-231-5029, Ext: 5630, Email: yama@clin.medic.mie-u.ac.jp
Haruyuki Takaki, MD, Phone: +81-59-231-5029, Ext: 5630, Email: takaki-h@clin.medic.mie-u.ac.jp
Atsuhiro Nakatsuka, MD, Sub-Investigator
Koichiro Yamakado, MD, Principal Investigator
Additional Information

Starting date: October 2009
Last updated: October 18, 2009

Page last updated: October 04, 2010

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