To Compare Intravitreal Clindamycin & Dexamethasone With Classic Treatment of Toxoplasmic Retinochoroiditis
Information source: Shaheed Beheshti Medical University
Information obtained from ClinicalTrials.gov on June 20, 2008
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Toxoplasmic Chorioretinitis
Intervention: Clindamycin+Dexamethasone (Drug); pyrimethamine-sulfadiazine + prednisolone (Drug)
Phase: Phase 2/Phase 3
Status: Recruiting
Sponsored by: Shaheed Beheshti Medical University Official(s) and/or principal investigator(s):
Masoud Soheilian, MD, Principal Investigator, Affiliation: Ophthalmic Research Center of Shaheed Beheshti Medical University
Overall contact:
Masoud Soheilian, MD, Phone: +98 21 22587317, Email: labbafi@hotmail.com
Summary
Toxoplasmosis, an intra cellular parasite, is a very important cause of chorioretinitis. The
goal of treatment is arresting multiplication of the parasite in its inflammatory active
phase. In this study we try to compare the efficacy of the classic regimen
(Pyrimethamine-Sulfadiazine + Prednisolon) with intravitreal Clindamycin & Dexamethasone.
Clinical Details
Study design: Treatment, Randomized, Single Blind, Active Control, Parallel Assignment, Safety/Efficacy Study
Eligibility
Minimum age: N/A.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Patients with Toxoplasmic chorioretinitis
- Location of the lesion within zone I of the retina or a lesion greater than 2DD with
3+-4+ vitreous inflammation in zone II or III
- No allergic history to the used drugs
- No any other diseases
Exclusion Criteria:
- Any allergic reaction to the used medications
- One eyed patients
- Partially treated patients
Locations and Contacts
Masoud Soheilian, MD, Phone: +98 21 22587317, Email: labbafi@hotmail.com
Ophthalmic Research Center, Tehran 16666, Iran, Islamic Republic of; Recruiting
Masoud Soheilian, MD, Phone: +98 21 22585952, Email: labbafi@hotmail.com
masoud Soheilian, MD, Principal Investigator
Additional Information
Starting date: July 2005
Last updated: October 6, 2006
|
