Study of Antibiotics in Cerebrospinal Fluid Following Intravenous Injection
Information source: Aarhus University Hospital
Information obtained from ClinicalTrials.gov on October 19, 2009
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Neurosurgery
Intervention: Vancomycin (Drug); Teicoplanin (Drug); Linezolid (Drug)
Phase: Phase 1
Status: Not yet recruiting
Sponsored by: Aarhus University Hospital
Summary
Three different antibiotics are used to prevent infection in case of neurosurgery - this
study examines to which extent the antibiotics penetrate from the blood to the cerebrospinal
fluid (surrounding the brain).
Clinical Details
Official title: Antibiotics in Cerebrospinal Fluid Following Intravenous Injection
Study design: Prevention, Randomized, Open Label, Active Control, Parallel Assignment, Pharmacokinetics Study
Eligibility
Minimum age: 18 Years.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Over 18 years old
- Already having an external CSF drain
- Scheduled for neurosurgery requiring antibiotic prophylaxis (most commonly placement
of an internal drain ("shunt")
Exclusion Criteria:
- Infection or colonization requiring other than standard prophylactic antibiotics
Locations and Contacts
Additional Information
Starting date: September 2009
Ending date: December 2011
Last updated: June 18, 2009
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