Effects of a Specific Spice on Energy Metabolism
Information source: University of Copenhagen
ClinicalTrials.gov processed this data on August 23, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Healthy
Intervention: Mustard (dijon) (Dietary Supplement); Placebo (Dietary Supplement)
Phase: N/A
Status: Completed
Sponsored by: University of Copenhagen Official(s) and/or principal investigator(s): Arne Astrup, Professor MD, Study Chair, Affiliation: Department of Human Nutrition, Faculty of Life Sciences, University of Copenhagen
Summary
The objective of this study is to examine whether a specific spice is capable of affecting
energy metabolism.
Since chili and other spices have been shown to increase energy expenditure and in some
cases also affect energy intake/appetite compared to placebo, the investigators expect that
the specific spice may actually increase energy expenditure and potentially also decrease
appetite - although not to a large degree.
Clinical Details
Official title: Effects of a Specific Spice on Energy Expenditure, Substrate Oxidation, Appetite and Energy Intake
Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Investigator, Outcomes Assessor), Primary Purpose: Prevention
Primary outcome: Energy expenditure (resting)/Meal-induced thermogenesis
Secondary outcome: VAS-scores for different appetite parameters (incl. satiety, hunger, fullness, prospective food intake, well-being, thirst etc.)Blood pressure Heart rate Substrate oxidation (fat and carbohydrate)
Detailed description:
Several pungent food ingredients, such as chili, and also other bioactive food ingredients,
e. g. green tea, have been shown to be able to increase energy expenditure and fat oxidation
during the hours following a meal containing the bioactive ingredient. Furthermore, we will
also look at the subjects own feelings of appetite and thereby examine whether the appetite
is affected by the spicy food, since a few studies have suggested an effect of bioactive
ingredients on appetite/energy intake. We expect to see some small effects on these
parameters.
Eligibility
Minimum age: 18 Years.
Maximum age: 50 Years.
Gender(s): Male.
Criteria:
Inclusion Criteria:
- male
- healthy and not using medication (regularly)
- normal weight
- non-smoker
- tolerate and like spicy food
- stable body weight last two months
Exclusion Criteria:
- increased blood pressure
- mental, metabolic and chronic diseases
Locations and Contacts
Department of Human Nutrition, Faculty of Life Sciences, university of Copenhagen, Frederiksberg C, Copenhagen DK-1958, Denmark
Additional Information
Starting date: August 2008
Last updated: February 10, 2009
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