Osteoporosis and Dental Implant
Information source: Charite University, Berlin, Germany
ClinicalTrials.gov processed this data on August 20, 2015
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Osteoporosis
Intervention: alendronate once weekly 70mg (Drug); placebo (Drug)
Phase: Phase 4
Status: Recruiting
Sponsored by: Charite University, Berlin, Germany Official(s) and/or principal investigator(s):
Dieter Felsenberg, Prof. D.r, Study Chair, Affiliation: Leader of the center for muscle and bone research, Charité
Overall contact:
Dieter Felsenberg, Prof. Dr., Phone: +490384453046, Email: dieter.felsenberg@charite.de
Summary
The purpose of this study is to evaluate the influence of alendronate therapy on the wound
healing after dental implants in patients with osteoporosis.
Clinical Details
Official title: Evaluation of the Influence of Alendronate on Wound Healing After Dental Implants in Patients With Osteoporosis
Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment
Primary outcome: Dental CT
Eligibility
Minimum age: 60 Years.
Maximum age: 75 Years.
Gender(s): Female.
Criteria:
Inclusion Criteria:
- Postmenopausal women > 2 years after menopause
- Age between 60 and 75 years
- Possibility to insert a dental implant
- Osteoporosis as defined by WHO criteria (intervention group), or women without
osteoporosis / osteopenia (non-intervention group)
Exclusion Criteria:
- Pathological findings in the jaw bone
- Chronic inflammatory rheumatoid disease
- Bisphosphonate treatments during the last 12 months
- Inflammatory or metabolic bone disease, excluding osteoporosis
- Systemic corticosteroid treatments of more than one month within previous 12 months
- Severe diseases with life expectancy less than one year or expectation of rapid
worsening within one year
Locations and Contacts
Dieter Felsenberg, Prof. Dr., Phone: +490384453046, Email: dieter.felsenberg@charite.de
Centre for Muscle and Bone Research, Charité - Campus Benjamin Franklin, Berlin 12200, Germany; Recruiting
Dieter Felsenberg, Prof. Dr., Phone: +493084453046
Hendrikje Boerst, Dipl. Wiss. org., Phone: +493084454745, Email: hendrikje.boerst@charite.de
Dieter Felsenberg, Prof. Dr., Principal Investigator
Anton ° Friedman, Dr., Sub-Investigator
Additional Information
Starting date: January 2004
Last updated: August 1, 2008
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