Effect of Nefazodone on Relapse in Females With Cocaine Abuse - 10
Information source: National Institute on Drug Abuse (NIDA)
Information obtained from ClinicalTrials.gov on June 20, 2008
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Cocaine-Related Disorders
Intervention: Nefazodone (Drug)
Phase: Phase 3
Status: Completed
Sponsored by: National Institute on Drug Abuse (NIDA) Official(s) and/or principal investigator(s):
Dorothy Hatsukami, Ph.D., Principal Investigator, Affiliation: University of Minnesota
Summary
The purpose of this study is to determine the effect of nefazodone on relapse to cocaine use
in depressed and non-depressed females with cocaine abuse/dependence.
Clinical Details
Official title: Effect of Nefazodone on Relapse in Females With Cocaine Abuse
Study design: Treatment, Double-Blind, Placebo Control
Primary outcome: RetentionPrimary drug use Depression (secondary) Relapse
Detailed description:
The purpose of this study is to determine the effect of nefazodone on relapse to cocaine in
women and if a greater effect will be seen in the dependent condition. A relapse and coping
skills questionnaire will be utilized to determine the various factors important to the
relapse process.
Eligibility
Minimum age: 18 Years.
Maximum age: 55 Years.
Gender(s): Female.
Criteria:
Inclusion Criteria:
Female, ages 18-55, cocaine abuse/dependence, use of cocaine 7 days of the last 30 days or
of the 30 days prior to current abstinence, less than 90 days current abstinence, at least
an 8th grade education.
Exclusion Criteria:
Unstable medical conditions; current use of Hismanal, Seldane, or Propulsid; dx of MR, OBS,
bipolar, schizophrenia.
Locations and Contacts
University of Minnesota, Minneapolis, Minnesota 55455, United States
Additional Information
Starting date: January 1999
Ending date: December 2001
Last updated: August 16, 2005
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