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A Comparison Study of Two Respiratory Physical Therapy Methods and Standard Medical Treatment for Treating COPD Patients During Acute Exacerbation

Information source: Sheba Medical Center
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Chronic Obstructive Pulmonary Disease; Chronic Bronchitis

Intervention: respiratory physical therapy manual technique- Autogenic Drainage (Procedure); respiratory physical therapy technique- IPV (Device)

Phase: N/A

Status: Not yet recruiting

Sponsored by: Sheba Medical Center

Overall contact:
Yaakov (kobi) Dagan, Msc., Phone: 0523694979, Email: kobi.dagan@sheba.health.gov.il


One of the main goals of the respiratory physical therapy is to help people who are suffering from accumulating of secretions in their airways and lungs. Chronic Obstructive Pulmonary Disease (COPD) patients are often hospitalized with an Acute Exacerbation of their medical condition. Those patients usually get only the standard medical care during the acute phase and don't get respiratory physical therapy treatment. The study's main aim is to investigate if respiratory physical therapy treatment in addition to standard medical care during the acute phase, can improve the respiratory and medical condition and reduce hospitalization stay. In order to do so we will compare three groups of COPD patients during acute exacerbation; two groups will get one out of two respiratory physical therapy techniques; manually or Intrapulmonary Percussive Ventilator (IPV) in addition to standard medical care and the third group will get standard medical care alone.

Clinical Details

Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator), Primary Purpose: Treatment

Primary outcome: length of stay in the hospital


Minimum age: 50 Years. Maximum age: 80 Years. Gender(s): Both.


Inclusion Criteria:

- clinical diagnosis of Acute Exacerbation of COPD or Acute Exacerbation of Chronic


- Respiratory Rate>25

- PaCO2> 45 mmHg

- 7. 35 < PH < 7. 38

Exclusion Criteria:

- intubation

- apnea

- glasgow coma scale < 8

- pneumothorax

- FEV1 < 50% predicted

- Ischemic Hearth Disease

Locations and Contacts

Yaakov (kobi) Dagan, Msc., Phone: 0523694979, Email: kobi.dagan@sheba.health.gov.il

Additional Information

Starting date: July 2014
Last updated: May 15, 2014

Page last updated: August 23, 2015

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