Comparison of Combination Antibiotics Eyedrop to Artificial Tear in Hordeolum After Incision and Curettage
Information source: Chulalongkorn University
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Hordeolum
Intervention: neomycin sulfate, polymyxin B sulfate and gramicidin (Drug); Artificial tear (Drug)
Phase: Phase 3
Status: Recruiting
Sponsored by: Chulalongkorn University Official(s) and/or principal investigator(s):
Parima Hirunwiwatkul, MD, Principal Investigator, Affiliation: Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University
Overall contact:
Parima Hirunwiwatkul, MD, Phone: 662-2564142, Ext: 205, Email: parima.H@chula.ac.th
Summary
To compare the effectiveness of combined antibiotic ophthalmic solution (neomycin sulfate,
polymyxin B sulfate and gramicidin) with placebo (artificial tear) in the treatment of
hordeolum after incision and curettage
Clinical Details
Official title: Dose Antibiotic Need in Hordeolum After Incision and Curettage? : A Randomized, Placebo-controlled Trial
Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
Primary outcome: Pain scale
Secondary outcome: Mass size and duration of cure
Detailed description:
Hordeolum is a common eyelid disease. In case of mass, I&C is required but role of
antibiotic after I&C is not clear. It may not need in post drainage period.
Eligibility
Minimum age: 18 Years.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- at least 5-millimeters hordeolum
- the onset within 7 days
Exclusion Criteria:
- previous incision and curettage of the same site within 1 month or more than 3 times
- lesions in the adjacent areas suggesting of complications associated with hordeolum
such as preseptal cellulitis or blepharitis
- The patients with immunodeficiency, history of bleeding tendency
- allergy to aminoglycoside, polymyxin B, gramicidin, xylocaine and povidone iodine
Locations and Contacts
Parima Hirunwiwatkul, MD, Phone: 662-2564142, Ext: 205, Email: parima.H@chula.ac.th
Department of Ophthalmology, Chulalongkorn University, Bangkok 10330, Thailand; Recruiting
Parima Hirunwiwatkul, MD, Phone: 662-2564142, Ext: 205, Email: parima.H@chula.ac.th
Puangphet Chalermphanich, MD, Phone: 662-256-4142, Ext: 207, Email: puangphet_c@yahoo.com
Parima Hirunwiwatkul, MD, Principal Investigator
Additional Information
Related publications: Hirunwiwatkul P, Wachirasereechai K. Effectiveness of combined antibiotic ophthalmic solution in the treatment of hordeolum after incision and curettage: a randomized, placebo-controlled trial: a pilot study. J Med Assoc Thai. 2005 May;88(5):647-50.
Starting date: September 2007
Last updated: November 22, 2010
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