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Prevalence of Clopidogrel (Plavix) Resistance in Hemodialysis Patients

Information source: North Shore Long Island Jewish Health System
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Cardiovascular Disease

Phase: N/A

Status: Completed

Sponsored by: North Shore Long Island Jewish Health System

Official(s) and/or principal investigator(s):
Suzanne El-Sayegh, MD, Principal Investigator, Affiliation: Staten Island University Hospital

Summary

The investigators are trying to find out if Clopidogrel (Plavix) is as effective in hemodialysis patients as in patients not hemodialysed.

Clinical Details

Official title: Prevalence of Clopidogrel (Plavix) Resistance in Hemodialysis Patients

Study design: Observational Model: Cohort, Time Perspective: Prospective

Primary outcome: Prevalence Of Plavix resistance

Secondary outcome: assess the risk factors for plavix resistance in the hemodialysis population

Detailed description: Cardiovascular disease is very frequent in hemodialysis patients. Lot of hemodialysis patients are on Clopidogrel (plavix). Their is some evidence that clopidogrel is not effective in hemodialysis as it is effective in patient without kidney problem. VerifyNow plavix is a machine that measure the ability of the blood to clot after giving plavix. We will collect blood from hemodialysis patients on plavix and check the ability of their blood to clot and thus indirectly measuring the efficacy of Plavix.

Eligibility

Minimum age: 18 Years. Maximum age: N/A. Gender(s): Both.

Criteria:

Inclusion Criteria:

- All patients on hemodialysis taking Plavix

Exclusion Criteria:

- known to have bleeding disorder

- Severely anemic with hemoglobin level (Hb) < 10g/dl

- Low Platelets < 10000

Locations and Contacts

Staten Island University Hospital, Staten Island, New York 10305, United States
Additional Information

Starting date: June 2010
Last updated: May 30, 2013

Page last updated: August 23, 2015

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