This study is being done to see if the blood pressure and metabolic effects of an approved
drug nebivolol is comparable to that of another approved drug hydrochlorothiazide (HCTZ) and
placebo in hypertensive patients.
All participants will also receive lisinopril, an angiotensin converting enzyme, or losartan,
an angiotensin receptor blocker. All medications are approved and marketed for the treatment
of hypertension. This study is being conducted in about 450 patients at approximately 60
research centers in the United States.
The study consists of approximately 9 study visits over a period of 5 months. During these
visits, patients will undergo routine health exams and some special laboratory tests such as
an oral glucose tolerance test.
Minimum age: 18 Years.
Maximum age: 80 Years.
Gender(s): Both.
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