Effect of Celecoxib on Transitional Pain After Outpatient Surgery
Information source: Lawson Health Research Institute
Information obtained from ClinicalTrials.gov on November 03, 2008
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Pain
Intervention: celebrex (Drug); placebo (Drug)
Phase: Phase 4
Status: Recruiting
Sponsored by: Lawson Health Research Institute Official(s) and/or principal investigator(s):
Ngozi Imasogie, MD, Principal Investigator, Affiliation: Lawson Health Research Institute
Overall contact:
Ngozi Imasogie, MD, Phone: 519-646-6000, Ext: 64219, Email: nimasog@uwo.ca
Summary
Sixty adults having shoulder and forearm surgery will receive either placebo or celebrex
started preoperatively and continued for 3 days. Rescue medications required as well as pain
scores will be assessed using a patient diary to evaluate the effect of celebrex in
controlling transitional pain
Clinical Details
Official title: Effect of Celecoxib on Transitional Pain After Outpatient Surgery
Study design: Treatment, Randomized, Double Blind (Subject, Investigator, Outcomes Assessor), Active Control, Parallel Assignment, Efficacy Study
Primary outcome: visual analogue score for pain
Secondary outcome: severity of nausea
Eligibility
Minimum age: 18 Years.
Maximum age: 65 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Patients scheduled for elective ambulatory surgery of the shoulder
- ASA I - III
- Able to read English
- Male or female
Exclusion Criteria:
- Allergy to local anesthetic, Cox2, sulpha drug, acetaminophen or oxycodone
- Women who are pregnant or lactating and women of childbearing age and not following
acceptable contraceptive precautions
- Any major medical or psychiatric problem
- Those with a known history of narcotic dependence, abuse or chronic narcotic intake
- Patients with known history of peptic ulcer or GI bleeding in the past, ulcers,
congestive heart failure, angina or previous heart attack, coagulation problems,
venous thrombosis, kidney or liver disease or strokes
Locations and Contacts
Ngozi Imasogie, MD, Phone: 519-646-6000, Ext: 64219, Email: nimasog@uwo.ca
St. Joseph's Health Care, London, Ontario N, Canada; Recruiting
Ngozi Imasogie, MD, Principal Investigator
Additional Information
Starting date: July 2004
Last updated: April 22, 2008
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