Intubation Time With Low Dose Rocuronium
Information source: Gachon University Gil Medical Center
ClinicalTrials.gov processed this data on August 23, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Intubation; Difficult
Intervention: Atropine (Drug); Normal saline (Drug)
Phase: N/A
Status: Completed
Sponsored by: Gachon University Gil Medical Center Official(s) and/or principal investigator(s): Jong Yeop Kim, MD,PhD, Study Director, Affiliation: Ajou University School of Medicine
Summary
The investigators hypothesized that increasing the cardiac output by use of atropine in
children might result in a reduction of the intubation time needed to facilitate tracheal
intubation.
Clinical Details
Official title: Study of Intubation Time Required for Excellent Tracheal Intubation With Low Dose Rocuronium During Propofol Anaesthesia in Children With and Without Atropine
Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator)
Primary outcome: intubation time
Detailed description:
The investigators hypothesized that increasing the cardiac output by use of atropine in
children might result in a reduction of the intubation time needed to facilitate tracheal
intubation. Therefore, the purpose of this study was to determine TimeEI with a low dose of
esmeron (rocuronium) (0. 3 mg. kg-1) for achievement of successful tracheal intubation
conditions during intravenous (i. v.) anaesthesia using propofol and alfentanil in children
and to determine whether administration of i. v. atropine (atropine sulphate) (10 μg. kg-1)
during anaesthesia induction reduced these times.
Eligibility
Minimum age: 3 Years.
Maximum age: 10 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- American Society of Anesthesiologists (ASA) physical status I,
- Tonsillectomy with adenoidectomy
Exclusion Criteria:
- Patients with known allergy to the drugs used in this study,
- A history of reactive airway disease and asthma,
- A neuromuscular disorder, an anticipated difficult airway, and
- Crying children on arrival in the operating theatre
Locations and Contacts
Gachon University Gil Medical Center, Incheon, Korea, Republic of
Additional Information
Related publications: Stoddart PA, Mather SJ. Onset of neuromuscular blockade and intubating conditions one minute after the administration of rocuronium in children. Paediatr Anaesth. 1998;8(1):37-40.
Starting date: May 2011
Last updated: November 1, 2011
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