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Intubation Time With Low Dose Rocuronium

Information source: Gachon University Gil Medical Center
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Intubation; Difficult

Intervention: Atropine (Drug); Normal saline (Drug)

Phase: N/A

Status: Completed

Sponsored by: Gachon University Gil Medical Center

Official(s) and/or principal investigator(s):
Jong Yeop Kim, MD,PhD, Study Director, Affiliation: Ajou University School of Medicine

Summary

The investigators hypothesized that increasing the cardiac output by use of atropine in children might result in a reduction of the intubation time needed to facilitate tracheal intubation.

Clinical Details

Official title: Study of Intubation Time Required for Excellent Tracheal Intubation With Low Dose Rocuronium During Propofol Anaesthesia in Children With and Without Atropine

Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Investigator)

Primary outcome: intubation time

Detailed description: The investigators hypothesized that increasing the cardiac output by use of atropine in children might result in a reduction of the intubation time needed to facilitate tracheal intubation. Therefore, the purpose of this study was to determine TimeEI with a low dose of esmeron (rocuronium) (0. 3 mg. kg-1) for achievement of successful tracheal intubation conditions during intravenous (i. v.) anaesthesia using propofol and alfentanil in children and to determine whether administration of i. v. atropine (atropine sulphate) (10 μg. kg-1) during anaesthesia induction reduced these times.

Eligibility

Minimum age: 3 Years. Maximum age: 10 Years. Gender(s): Both.

Criteria:

Inclusion Criteria:

- American Society of Anesthesiologists (ASA) physical status I,

- Tonsillectomy with adenoidectomy

Exclusion Criteria:

- Patients with known allergy to the drugs used in this study,

- A history of reactive airway disease and asthma,

- A neuromuscular disorder, an anticipated difficult airway, and

- Crying children on arrival in the operating theatre

Locations and Contacts

Gachon University Gil Medical Center, Incheon, Korea, Republic of
Additional Information

Related publications:

Stoddart PA, Mather SJ. Onset of neuromuscular blockade and intubating conditions one minute after the administration of rocuronium in children. Paediatr Anaesth. 1998;8(1):37-40.

Starting date: May 2011
Last updated: November 1, 2011

Page last updated: August 23, 2015

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