Comparison of Preincisional Infiltrated Dexmedetomidine and Lidocaine Plus Adrenaline for Nasal Sephoplasty Surgery.
Information source: TC Erciyes University
ClinicalTrials.gov processed this data on August 23, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Surgery; Pain
Intervention: Dexmedetomidine (Drug); Lidocaine (Drug); Adrenaline (Drug)
Phase: Phase 4
Status: Completed
Sponsored by: TC Erciyes University Official(s) and/or principal investigator(s): Adnan Bayram, MD, Principal Investigator, Affiliation: Erciyes University
Summary
It is very important to decrease the bleeding during nasal septoplasty in order to increase
the visibility of the surgical site. Our primary goal was to investigate the effects of
dexmedetomidine and lidocaine plus adrenaline on visibility of surgical site and
postoperative analgesic consumption.
Clinical Details
Official title: Phase 4 Study of Comparison of Preincisional Infiltrated Dexmedetomidine and Lidocaine Plus Adrenaline for Surgical Conditions and Postoperative Analgesic Consumption in Nasal Sephoplasty Surgery.
Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention
Primary outcome: surgical conditions
Secondary outcome: Analgesic Consumption
Detailed description:
Nasal septoplasty is a surgery procedure which needs to have decrease the bleeding during
the surgery for the visibility of surgical site. And postoperative pain is very usual after
the surgery, so an effective postoperative analgesia procedure reduces the complications and
helps to be discharged earlier from the hospital. An alpha 2 agonist Dexmedetomidine has an
analgesic effect and vasoconstructive effect on the periferal blood vessels. Our hypothesis
was dexmedetomidine makes a better surgecal conditions during the surgery and reduce the
postoperative analgesic consumption. We administered the infiltrated dexmedetomidine or
lidocaine plus adrenaline to the both side of the nasal septum 10 minutes before the
surgery. Bleeding scores (Fromm and Boezaart Bleeding Scores) were recorded during the
surgery. And postoperative analgesic consumptions were recorded in first 24 hours after the
surgery.
Eligibility
Minimum age: 18 Years.
Maximum age: 60 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Scheduled for the nasal septoplasty surgery
- ASA 1-2 patients
- 18-60 yo patients
Exclusion Criteria:
- Pregnant patients
- ASA 3-4 patients
- Under 18 yo childrens
Locations and Contacts
Additional Information
Starting date: March 2013
Last updated: October 15, 2013
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