Effects of Nefazodone on Treatment of Female Cocaine Abusers - 3

Condition(s) targeted: Cocaine-Related Disorders

Intervention: Nefazodone (Drug)

Phase: Phase 2

Status: Completed

Sponsored by: National Institute on Drug Abuse (NIDA)

Official(s) and/or principal investigator(s):
Dorothy Hatsukami, Ph.D., Principal Investigator, Affiliation: University of Minnesota

The purpose of this study is to determine the effects of nefazedone on cocaine self-administration in depressed and non-depressed female cocaine users.

Official title: Effects of Nefazodone on Treatment of Female Cocaine Abusers

Study design: Treatment, Double-Blind, Placebo Control

Primary outcome:

Craving

Drug use

Depression

Life functioning

HIV risk behaviors

Detailed description: This study evaluated the effect of nefazodone on reducing cocaine use and craving in both depressed and nondepressed women and if there was a greater effect in depressed women.

Minimum age: 18 Years. Maximum age: 55 Years. Gender(s): Female.

Criteria:

Inclusion Criteria:

Females, ages 18-55, minimum use of 8 days of the last 30, minimum of 8th grade education, current diagnosis of cocaine abuse/dependence

Exclusion Criteria:

Unstable medical illness, dx of MR, OBS, bipolar

University of Minnesota, Minneapolis, Minnesota 55455, United States

Starting date: December 1996
Ending date: December 2001
Last updated: August 16, 2005