Effects of Roaccutane on Ca, P, PTH and Vitamin D Metabolites in the Treatment of Sever Acne
Information source: Shaheed Beheshti Medical University
Information obtained from ClinicalTrials.gov on June 20, 2008
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Acne
Intervention: isotretinoin (Roaccutane) (Drug)
Phase: Phase 1
Status: Completed
Sponsored by: Shaheed Beheshti Medical University Official(s) and/or principal investigator(s):
parviz toossi, md, Study Chair, Affiliation: Skin Research Center
Hamideh Moravvej, md, Principal Investigator, Affiliation: Skin Research Center
Nahid Mohtasham, md, Principal Investigator, Affiliation: Skin Research Center
Summary
serum levels Ca, P, PTH and vitamin D metabolites before and after treatment with
isotretinoin for sever acne
Clinical Details
Official title: Effects of Roaccutane on Ca, P, PTH and Vitamin D Metabolites in the Treatment
Study design: Treatment, Randomized, Open Label, Dose Comparison, Single Group Assignment, Safety/Efficacy Study
Primary outcome: serum levels of Ca, P, PTH and vitamin D metabolites and lateral chest x-ray before the treatment
Secondary outcome: serum levels of Ca, P, PTH and vitamin D metabolites and lateral chest x-ray after the treatment
Detailed description:
few studies has been done of serum levels Ca, P, PTH and vitamin D metabolites in patients
receiving isotretinoin .In this study we measured serum levels Ca, P, PTH and vitamin D
metabolites before and after treatment with isotretinoin for sever acne in 30 patients . the
patients had no kown skeletal, endocrine ,renal and gastrointestinal disorders.
Eligibility
Minimum age: N/A.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- sever acne
Exclusion Criteria:
- renal disorders
- gastrointestinal disorders
- skeletal disorders
- endocrine disorders
- drugs such as glucocorticoids , thiazide diuretics, mineral multivitamins, anti acids,
tetracyclines
Locations and Contacts
Shaheed Beheshti Medical University, Skin research center, Tehran 198994148, Iran, Islamic Republic of
Additional Information
Starting date: October 2005
Ending date: November 2006
Last updated: January 22, 2008
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