DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more



Predictive Value of Dynamic Contrast Enhancement MRI on a Cerebral Tumor Response to Gamma Knife Treatment

Information source: Université de Sherbrooke
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Cerebral Metastases

Phase: N/A

Status: Completed

Sponsored by: Martin Lepage

Official(s) and/or principal investigator(s):
Jean Chenard, MD, Principal Investigator, Affiliation: University of Sherbrooke

Summary

Hypothesis: the pattern of MRI contrast enhancement after gadolinium injection is different in tumors that respond well to gamma knife. We are going to acquire sequential T1-weighted images of brain lesions before, during and after injection of Gd-DTPA. This will be repeated before and after a treatment with gamma knife. We will then analyse our results to see if there are common enhancement characteristics between lesions that will respond well to the radiosurgery treatment. Response will be clinically assessed by tumor volume as determined by MRI approximately 4 to 6 months after treatment.

Clinical Details

Official title: Prospective Study of Predictive Value of Dynamic Contrast Enhancement Magnetic Resonance Imaging With Gadolinium on the Response of a Cerebral Tumor to a Treatment With Gamma Knife

Study design: Observational Model: Case-Only, Time Perspective: Prospective

Primary outcome: MRI parameters

Eligibility

Minimum age: 18 Years. Maximum age: N/A. Gender(s): Both.

Criteria:

Inclusion Criteria:

- Patient with intracerebral lesion benign or malignant wich are not concerned by the

exclusion criteria Exclusion Criteria:

- Pancranial radiotherapy

- Residual postop lesion

- Gliomas

- Patients < 18 years old

- Anterior allergic reaction to gadolinium

- Claustrophobia.

Locations and Contacts

Faculté de médecine, Université de Sherbrooke, Sherbrooke, Quebec J1H 5N4, Canada
Additional Information

Starting date: August 2005
Last updated: January 13, 2015

Page last updated: August 23, 2015

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017