High-resolution Imaging of Corneal Lesions With Optical Coherence Tomography (OCT) - A Pilot Study
Information source: Medical University of Vienna
ClinicalTrials.gov processed this data on August 20, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Corneal Abrasions; Corneal Infiltrates
Intervention: Optical Coherence Tomography (OCT) (Device); Slit lamp biomicroscopy (Other)
Phase: N/A
Status: Recruiting
Sponsored by: Medical University of Vienna Overall contact: Gerhard Garhoefer, MD, Phone: +43140400, Ext: 2981, Email: gerhard.garhoefer@meduniwien.ac.at
Summary
Corneal lesions such as corneal abrasions and corneal infiltrates are common in clinical
practice. The current study seeks to investigate whether high-resolution OCT is suitable for
imaging of these corneal lesions. The present study has the character of a pilot study and
the results are intended to be used to develop a standardized protocol for imaging and
analysis of these corneal lesions. Based on this protocol, further studies investigating the
pathophysiology of corneal lesions or evaluating therapeutic success can be planned.
Clinical Details
Official title: High-resolution Imaging of Corneal Lesions With Optical Coherence Tomography (OCT) - A Pilot Study
Study design: Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Basic Science
Primary outcome: Imaging of corneal abrasions and infiltrates
Secondary outcome: Size and depth of corneal lesions as assessed with high-resolution OCTSlit lamp biomicroscopy with fluorescein staining
Eligibility
Minimum age: 18 Years.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Men and women aged over 18 years
- Newly diagnosed corneal abrasion or corneal infiltrate
Exclusion Criteria:
- Recurrent corneal erosion
- Participation in a clinical trial in the previous 3 weeks
- Presence of any abnormalities preventing reliable measurements as judged by the
investigator
- Any contraindication for topical application of Novain 0. 4% eye drops for topical
anesthesia or of Minims-Fluorescein Sodium eye drops for fluorescein staining
- Pregnancy, planned pregnancy or lactating
Locations and Contacts
Gerhard Garhoefer, MD, Phone: +43140400, Ext: 2981, Email: gerhard.garhoefer@meduniwien.ac.at
Department of Clinical Pharmacology, Medical University of Vienna, Vienna 1090, Austria; Recruiting Gerhard Garhoefer, MD, Phone: +43140400, Ext: 2981, Email: gerhard.garhoefer@meduniwien.ac.at Katarzyna Napora, MD, Principal Investigator
Additional Information
Starting date: July 2013
Last updated: November 12, 2014
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