DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Methadone Maintenance for Prisoners

Information source: Friends Research Institute, Inc.
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Heroin Addiction

Intervention: Counseling Only (Other); Counseling + Transfer (Drug); Counseling + Methadone (Drug)

Phase: Phase 3

Status: Completed

Sponsored by: Friends Research Institute, Inc.

Official(s) and/or principal investigator(s):
Timothy W Kinlock, Ph.D., Principal Investigator, Affiliation: Friends Research Institute, Inc.


This five-year study examines the benefits of methadone maintenance treatment initiated in prison and continued in the community to male offenders who were previously, but not currently, heroin-dependent. It is anticipated that such prisoners will have more favorable outcomes in the year following release with regard to drug abuse, crime, and HIV risk behavior than either prisoners who receive counseling only or begin initiation of methadone maintenance in the community

Clinical Details

Official title: Methadone Maintenance for Prisoners

Study design: Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Primary outcome:

Treatment Retention in the Community

Heroin Use

Cocaine Use

HIV-risk Behaviors

Criminal Activity

Secondary outcome: Employment

Detailed description: Most prisoners with histories of pre-incarceration heroin addiction do not receive treatment while incarcerated or upon release. Effective treatment for such prisoners is urgently needed because rapid relapse typically follows release. Relapse is associated with increased risk for HIV, overdose death, criminal activity, and reincarceration. Other than three studies of methadone maintenance with short-term jail inmates, the only study of longer-term inmates who were previously, but not currently, heroin-dependent was the investigator's pilot study with pre-release inmates. Based on that pilot study, which found that initiating maintenance treatment is feasible and facilitates post-release treatment entry, the present study provides a more rigorous examination of this unique treatment approach.


Minimum age: 18 Years. Maximum age: 65 Years. Gender(s): Male.


Inclusion Criteria:

- Heroin dependence in the year prior to current incarceration

- 3-6 months left to serve in prison-male pre-release inmate suitability for methadone

maintenance as determined by medical evaluation

- Willingness to enroll in methadone maintenance

- Having a Baltimore address

Exclusion Criteria:

- Pending parole hearing

- Pending charges

- Kidney failure

- Liver failure

Locations and Contacts

Metropolitan Transition Center, Baltimore, Maryland 21201, United States
Additional Information

Related publications:

Kinlock TW, Schwartz RP, Gordon MS. The significance of interagency collaboration in developing opioid agonist programs for inmates. Corrections Compendium 30(3)6-9,28-30,2005.

Starting date: September 2003
Last updated: April 1, 2014

Page last updated: August 23, 2015

-- advertisement -- The American Red Cross
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017