A Comparison Between Propofol and Etomidate in Hysteroscopy on Effect of Postoperative Sedation and Cognitive Function in Elderly Patients
Information source: Shaanxi Provincial People's Hospital
ClinicalTrials.gov processed this data on August 23, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Hysteroscopy; Hemodynamics; Sedation
Intervention: Etomidate (Drug); Propofol (Drug); Remifentanil (Drug); Anesthesia induction (Drug)
Phase: Phase 4
Status: Not yet recruiting
Sponsored by: Shaanxi Provincial People's Hospital Overall contact: Wenying Song, Phone: +86-13609245447, Email: swysong2010@126.com
Summary
To compare the effect of propofol and etomidate in hysteroscopy on postoperative sedation
and cognitive function in elderly patients
Clinical Details
Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
Primary outcome: Heart rateMean arterial pressure Pulse oxygen saturation Respiratory rate Narcotrend index
Secondary outcome: Cerebral injury parametersLength of stay Score of Minimum Mental State Examination Verbal Fluency test
Eligibility
Minimum age: 60 Years.
Maximum age: 80 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
1. Aged between 60 and 80 years
2. Selective hysteroscopic operation
3. American Society of Anesthesiology (ASA) Physical Status: Ⅰ or Ⅱ
4. Signed informed consent form
5. Expected operation duration is within 60 minutes
Exclusion Criteria:
1. Serious cardiac, cerebral, liver, kidney, lung, endocrine disease or sepsis
2. Long use of hormone or history of adrenal suppression
3. Allergy to trial drug or other contraindication
4. History or expected difficult airway
5. Identified, suspected abuse or long use of narcotic analgesia
6. Neuromuscular diseases
7. Mentally unstable or has a mental illness
8. Dysfunction of communication
9. Trend of malignant hyperthermia
10. Pregnant or breast-feeding women
11. Attended other trial past 30 days;
Locations and Contacts
Wenying Song, Phone: +86-13609245447, Email: swysong2010@126.com Additional Information
Starting date: December 2014
Last updated: May 27, 2014
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