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A Comparison Between Propofol and Etomidate in Hysteroscopy on Effect of Postoperative Sedation and Cognitive Function in Elderly Patients

Information source: Shaanxi Provincial People's Hospital
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Hysteroscopy; Hemodynamics; Sedation

Intervention: Etomidate (Drug); Propofol (Drug); Remifentanil (Drug); Anesthesia induction (Drug)

Phase: Phase 4

Status: Not yet recruiting

Sponsored by: Shaanxi Provincial People's Hospital

Overall contact:
Wenying Song, Phone: +86-13609245447, Email: swysong2010@126.com

Summary

To compare the effect of propofol and etomidate in hysteroscopy on postoperative sedation and cognitive function in elderly patients

Clinical Details

Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Primary outcome:

Heart rate

Mean arterial pressure

Pulse oxygen saturation

Respiratory rate

Narcotrend index

Secondary outcome:

Cerebral injury parameters

Length of stay

Score of Minimum Mental State Examination

Verbal Fluency test

Eligibility

Minimum age: 60 Years. Maximum age: 80 Years. Gender(s): Both.

Criteria:

Inclusion Criteria: 1. Aged between 60 and 80 years 2. Selective hysteroscopic operation 3. American Society of Anesthesiology (ASA) Physical Status: Ⅰ or Ⅱ 4. Signed informed consent form 5. Expected operation duration is within 60 minutes Exclusion Criteria: 1. Serious cardiac, cerebral, liver, kidney, lung, endocrine disease or sepsis 2. Long use of hormone or history of adrenal suppression 3. Allergy to trial drug or other contraindication 4. History or expected difficult airway 5. Identified, suspected abuse or long use of narcotic analgesia 6. Neuromuscular diseases 7. Mentally unstable or has a mental illness 8. Dysfunction of communication 9. Trend of malignant hyperthermia 10. Pregnant or breast-feeding women 11. Attended other trial past 30 days;

Locations and Contacts

Wenying Song, Phone: +86-13609245447, Email: swysong2010@126.com

Additional Information

Starting date: December 2014
Last updated: May 27, 2014

Page last updated: August 23, 2015

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