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Immediate Effects of Upper Thoracic Manipulation on Skin Surface Temperature of T3 Vertebral Region and Biceps Brachii Muscle

Information source: Universidade Metodista de Piracicaba
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Myofascial Dysfunction

Intervention: Spine manipulation (Other); Manipulation sham (Other)

Phase: N/A

Status: Completed

Sponsored by: Universidade Metodista de Piracicaba

Official(s) and/or principal investigator(s):
Amanda Packer, MSc, Principal Investigator, Affiliation: Universidade Metodista de Piracicaba


The aim of the present study was to assess the immediate effects of upper thoracic manipulation on skin surface temperature in the region of the T3 vertebra and biceps brachii muscle in healthy women. It is a randomized controlled blind study. Twenty-six healthy women of the university community were randomly allocated to an experimental group (n = 13) and a placebo group (n = 13). A single session of the upper thoracic spine manipulation (segment T3)was performed. Infrared thermography was used to determine changes in skin surface temperature in the region of T3 and the biceps brachii muscle, which would indirectly reflect sympathetic activity. Images were taken prior to manipulation, immediately after and both five and 10 minutes after manipulation. Repeated measures ANOVA with the post hoc Bonferroni test and the independent samples t-test were used for the intragroup and intergroup comparisons, respectively, with the level of significance set to 5%.

Clinical Details

Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment

Primary outcome: Skin temperature


Minimum age: 18 Years. Maximum age: 30 Years. Gender(s): Female.


Inclusion Criteria:

- Healthy women

- 18 and 30 years of age

Exclusion Criteria:

- use of vasoactive medication

- body mass index greater than 25 kg/m2

- having undergone spinal manipulation in previous month

- and any red flag sign, such as malignant tumor, inflammatory or infectious disease

that contraindicated manual therapy

Locations and Contacts

Methodist University of Piracicaba, Piracicaba, São Paulo 13.423-170, Brazil
Additional Information

Starting date: January 2011
Last updated: June 4, 2013

Page last updated: August 23, 2015

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