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Intravenous-Morphine and Glucagon-Usage Enhanced MR Cholangiography

Information source: National Taiwan University Hospital
Information obtained from ClinicalTrials.gov on October 19, 2009
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Liver Disease

Intervention: morphine and glucagon (Drug)

Phase: Phase 4

Status: Recruiting

Sponsored by: National Taiwan University Hospital

Official(s) and/or principal investigator(s):
Hon-Man Liu, MD, Study Chair, Affiliation: National Taiwan University Hospital

Overall contact:
Yuan-Heng Mo, MD, Email: jamesmyh@ha.mc.ntu.edu.tw

Summary

Morphine can induce constriction of sphincter of oddi and glucagon can facilitate bile secretion and dilatation of bile duct. We conduct this randomized double blinded study to evaluate the effect of enhancement in MRCP using intravenous morphine and glucagon.

Clinical Details

Study design: Diagnostic, Randomized, Double-Blind, Uncontrolled, Parallel Assignment

Primary outcome: MRCP visibility

Detailed description: Morphine can induce constriction of sphincter of oddi and glucagon can facilitate bile secretion and dilatation of bile duct. We conduct this randomized double blinded study to evaluate the effect of enhancement in MRCP using intravenous morphine and glucagon.

Eligibility

Minimum age: 20 Years. Maximum age: 75 Years. Gender(s): Both.

Criteria:

Inclusion Criteria:

- normal volunteer

- living liver donor

Exclusion Criteria:

- COPD

- chronic liver disease

- hypersensitive to glucagon

- DM

- insulinoma

- glucagonoma

- pregnancy

Locations and Contacts

Yuan-Heng Mo, MD, Email: jamesmyh@ha.mc.ntu.edu.tw

National Taiwan University Hospital, Taipei, province of Taiwan 100, Taiwan; Recruiting
Yuan-Heng Mo, MD, Email: jamesmyh@ha.mc.ntu.edu.tw
Additional Information

Starting date: September 2005
Ending date: September 2005
Last updated: November 25, 2005

Page last updated: October 19, 2009

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