Dexmedetomidine Influence on the Level of Perioperative Blood Glucose and Insulin of Elderly Diabetes Patients
Information source: Second Affiliated Hospital of Xi'an Jiaotong University
ClinicalTrials.gov processed this data on August 23, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Perioperative Blood Glucose and Insulin
Intervention: general anesthesia induction (Drug); Isoflurane (Drug); Dexmedetomidine (Drug); normal saline (Drug)
Phase: Phase 4
Status: Recruiting
Sponsored by: Second Affiliated Hospital of Xi'an Jiaotong University Overall contact: Hongtao Liu, Phone: 13572225310, Email: lannylouis@163.com
Summary
Dexmedetomidine is a kind of high selectivity alpha 2 agonists adrenaline, can inhibit the
activity of sympathetic nerve, alleviate pain,and improve cardiovascular stability in the
operation period. Dexmedetomidine have influence on perioperative stress response and immune
function,but it is not clear.
Clinical Details
Study design: Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Primary outcome: blood glucoselevel of blood insulin
Secondary outcome: vital signs
Eligibility
Minimum age: 60 Years.
Maximum age: 80 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Aged 60 to 80 years old;
- Type 2 diabetes;
- Not use insulin treatment;
- Onging general anesthesia surgery;
- Surgery time 1-3 hours
Exclusion Criteria:
- ASA classification > class II;
- Hypertension;
- Serious central nervous system diseases (acute stroke, uncontrolled seizures, -Severe
dementia);
- Unstable angina and acute myocardial infarction;
- Allergy to investigational drug;
- Hepatic and renal dysfunction
Locations and Contacts
Hongtao Liu, Phone: 13572225310, Email: lannylouis@163.com
SecondXianJiaotongU, Xi'an, Shanxi, China; Recruiting Hongtao Liu, Phone: 13572225310, Email: lannylouis@163.com
Additional Information
Starting date: May 2014
Last updated: May 30, 2014
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