Visceral Pain From the Upper Urinary Tract - a Trial on the Effect of Morphine and Oxycodone in Patients Undergoing Percutaneous Nephrolithotomy (PCNL)
Information source: Fredericia Hosptial
Information obtained from ClinicalTrials.gov on October 19, 2009
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Kidney Stones
Intervention: oxycodone (Drug); morphine (Drug)
Phase: Phase 3
Status: Recruiting
Sponsored by: Fredericia Hosptial Official(s) and/or principal investigator(s):
Palle Osther, Professor, Study Chair, Affiliation: Hospital Little Belt, Fredericia
katja Venborg Pedersen, MD, Principal Investigator, Affiliation: Hospital Little Belt, Fredericia
Overall contact:
Katja venborg pedersen, MD, Phone: 0045 76237339, Email: katjavenborg@yahoo.dk
Summary
The purpose of this study is to investigate the effect of oxynorm versus morphine after
operation for kidney stone (PCNL). In addition the relationship between pain symptoms and
referred sensory and trophic changes will be examined in the patients before and after the
operation. Finally a blood sample is analysed to investigate pharmaca-genetics.
Clinical Details
Official title: Visceral Pain Originating From the Upper Urinary Tract - a Randomized Controlled Trial on the Effect of Morphine and Oxycodone in Patients Undergoing Percutaneous Nephrolithotomy (PCNL)
Study design: Treatment, Randomized, Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Active Control, Parallel Assignment, Efficacy Study
Primary outcome: Amount of analgetics used
Secondary outcome: Side effects
Eligibility
Minimum age: 18 Years.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Age > 18
- Indication for PCNL
Exclusion Criteria:
- Malignant disease in the upper urinary tract
- Allergy to morphine or oxycodone
- Use of opioids the last 48 hours before PCNL
- Pregnancy
- Nursing mothers
- Present JJ-stent in the ureter
- Previous urinary stone disease on the opposite site
Locations and Contacts
Katja venborg pedersen, MD, Phone: 0045 76237339, Email: katjavenborg@yahoo.dk
Hospital Little Belt, Fredericia, Fredericia 7000, Denmark; Recruiting
katja venborg Pedersen, MD, Phone: 0045 76237339, Email: katjavenborg@yahoo.dk
Katja venborg Pedersen, MD, Principal Investigator
Additional Information
Starting date: December 2008
Ending date: December 2010
Last updated: August 3, 2009
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