Treatment of Early Nasal Polyposis With Topical Triamcinolone
Information source: Steward St. Elizabeth's Medical Center of Boston, Inc.
ClinicalTrials.gov processed this data on August 23, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Nasal Polyps
Intervention: Triamcinolone (Drug); Triamcinolone (Drug)
Phase: Phase 2
Status: Terminated
Sponsored by: Steward St. Elizabeth's Medical Center of Boston, Inc. Official(s) and/or principal investigator(s): Peter Catalano, MD, Study Director, Affiliation: Steward St. Elizabeth's Medical Center of Boston, Inc.
Summary
The purpose of this study is to compare the effectiveness of intranasal Triamcinolone
delivered through a bio-absorbable nasal dressing verses oral steroids and a saline soaked
dressing, in the treatment and prevention of early nasal polyposis.
Clinical Details
Official title: Treatment of Early Nasal Polyposis With Topical Triamcinolone
Study design: Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Primary outcome: To evaluate the efficacy of a Nasopore dressing soaked in Triamcinolone verses oral steroids and a saline soaked sponge
Detailed description:
Nasopore, a bio-absorbable nasal dressing, may offer an alternative route of sustained
steroid drug delivery. The use of topical targeted intranasal steroids may prevent the
routine adverse effects of oral steroids while maintaining the same therapeutic / clinical
efficacy.
Eligibility
Minimum age: 18 Years.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Age > 18 years
- Patients with early nasal polyposis
Exclusion Criteria:
- Age < 18 years
- Patients with active sinus infections
- Patients on long term steroids
- Allergy or sensitivity to steroids
- Patients with Antrochoanal polyps
- Patients who received topical steroids by bio-resorbable sponge or oral steroids
Locations and Contacts
St. Elizabeth's Medical Center, 736 Cambridge St, Brighton, Massachusetts 02135, United States
Additional Information
Starting date: July 2010
Last updated: January 2, 2014
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