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Adjunctive Atropine During Ketamine Sedation

Information source: Seoul National University Hospital
Information obtained from ClinicalTrials.gov on December 08, 2011
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Conscious Sedation

Intervention: Atropine (Drug)

Phase: Phase 4

Status: Recruiting

Sponsored by: Seoul National University Hospital

Overall contact:
Jin Hee Lee, Professor, Phone: +82-31-787-7575, Email: gienee@snubh.org

Summary

- Ketamine seems an obvious choice in the setting of an emergency department

- Ketamine leads to increased production of salivary and tracheal secretions

- Antisialagogues(atropine)therefore have been recommended as a routine adjunct

- We compare atropine with placebo as an adjunct to ketamine sedation in children

undergoing primary closure of lacerated wound

Clinical Details

Official title: Is Atropine Needed With Ketamine Sedation?

Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment

Primary outcome: Hypersalivation(VAS)

Secondary outcome:

Sedation scale

Pain scale

Complication

Satisfaction of parents and clinicians

Eligibility

Minimum age: 12 Months. Maximum age: 10 Years. Gender(s): Both.

Criteria:

Inclusion Criteria:

- Pediatric lacerated patients

Exclusion Criteria:

- Contraindication of ketamine or atropine

Locations and Contacts

Jin Hee Lee, Professor, Phone: +82-31-787-7575, Email: gienee@snubh.org

Seoul National University Bundang Hospital, Gyeonggi-do 463-707, Korea, Republic of; Recruiting
Jin Hee Lee, Professor, Phone: +82-31-787-7575, Email: gienee@snubh.org
Jin Hee Lee, Professor, Principal Investigator
Kyuseok Kim, Professor, Sub-Investigator
Joong Eui Rhee, Professor, Sub-Investigator
Tae Yun Kim, Professor, Sub-Investigator
You Hwan Jo, Professor, Sub-Investigator
Additional Information

Starting date: August 2008
Last updated: February 1, 2009

Page last updated: December 08, 2011

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