DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more



Tadalafil and Acetazolamide Versus Acetazolamide in Acute Mountain Sickness Prevention

Information source: Sheba Medical Center
Information obtained from ClinicalTrials.gov on December 08, 2011
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Pulmonary Edema; Cerebral Edema

Intervention: Tadalafil and acetazolamide (Drug); Acetazolamide (Drug)

Phase: N/A

Status: Recruiting

Sponsored by: Sheba Medical Center

Summary

To evaluate the additive value of tadalafil given together with Diamox (acetazolamide) in preventing acute mountain sickness in travelers to high altitude areas.

Clinical Details

Official title: Tadalafil and Acetazolamide Versus Acetazolamide in Acute Mountain Sickness Prevention

Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Primary outcome: Results will be evaluated by using the Lake Louise AMS scoring system

Detailed description: A randomized controlled study comparing:

Tadalafil [20mg x1/day] and acetazolamide [125mg x2 day], versus Acetazolamide [125mg x2 day] alone, in trekkers to altitude > 3,000 m.

Eligibility

Minimum age: 18 Years. Maximum age: N/A. Gender(s): Both.

Criteria:

Inclusion Criteria:

- Participant in trekking to high altitude

- Agreement to sign the informed consent.

Exclusion Criteria:

- No agreement to sign informed consent.

Locations and Contacts

Center of Geographic Medicine, Tel Hashomer, Israel; Recruiting
eli Schwartz, MD, Phone: 03-5302422, Email: elischwa@post.tau.ac.il
Eli Schwartz, MD, Principal Investigator
Eyal Leshem, MD, Sub-Investigator

Sheba Medical Ctr., Tel Hashomer, Israel; Recruiting
Eli Schwartz, MD, Phone: 03-5302168, Email: elischwa@post.tau.ac.il
Eyal lershem, MD, Phone: 03-5303500, Email: leshem@gmail.com

Tel Hashomer, Israel; Recruiting
Eli Schwartz, MD, Phone: 03-5302168
Eyal Leshem, MD, Phone: 03-5303500
Schwartz Eli, MD, Principal Investigator
Eyal leshem, MD, Sub-Investigator

Additional Information

Starting date: January 2006
Last updated: February 1, 2010

Page last updated: December 08, 2011

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2014