Topical Radial Artery Vasodilation
Information source: University of California, San Francisco
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Cardiac Catheterization; Spasm
Intervention: Nitroglycerin and lidocaine (Drug); Placebo (Other)
Phase: Phase 2/Phase 3
Status: Completed
Sponsored by: University of California, San Francisco Official(s) and/or principal investigator(s):
Andrew Boyle, MBBS, PhD, Principal Investigator, Affiliation: University of California, San Francisco
Summary
The aim of the study is to facilitate radial artery access for cardiac catheterization. The
investigators hypothesize that topical nitroglycerin and lidocaine will reduce radial artery
spasm. Patients undergoing cardiac catheterization via the radial artery will be randomized
to topical nitroglycerin + lidocaine versus placebo.
Clinical Details
Official title: The Effect of Topical Administration of Lidocaine/Nitroglycerin Combination Versus Placebo on Radial Artery Access in Patients Undergoing Cardiac Catheterization Via the Radial Artery
Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment
Primary outcome: Change in Radial Artery Diameter
Secondary outcome: Radial Artery Spasm During CatheterizationRadial Artery Patency
Detailed description:
The aim of the study is to facilitate radial artery access for cardiac catheterization. The
investigators hypothesize that topical nitroglycerin and lidocaine will reduce radial artery
spasm. Patients undergoing cardiac catheterization via the radial artery will be randomized
to topical nitroglycerin + lidocaine versus placebo.
Eligibility
Minimum age: 18 Years.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Undergoing trans-radial cardiac catheterization
Exclusion Criteria:
- inability to receive nitroglycerin or lidocaine due to allergy or medication
interactions
Locations and Contacts
University of California San Francisco Medical Center, San Francisco, California 94143, United States
Additional Information
Starting date: July 2010
Last updated: May 16, 2013
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