Patient's Anastrozole Compliance to Therapy Programme

Condition(s) targeted: Breast Cancer

Intervention: Anastrozole (Drug)

Phase: N/A

Status: Recruiting

Sponsored by: AstraZeneca

Official(s) and/or principal investigator(s):
AstraZeneca Germany Medical Director, Study Director, Affiliation: AstraZeneca

Overall contact:
AstraZeneca Germany Clinical Study, Information, Phone: +49 4103-708-3814, Email: brigette.gutendorf@astrazeneca.com

Approximately 60 specialised clinics and 420 office based gynaecologists or oncologists will participate in this in practice evaluation program (NIS). The clinic and approximately 7 office based physicians will collaborate within their breast centre networks to conduct this program. A breast centre network should be able to recruit in this program approximately 80 patients (approximately 40 patients per year). It is planned to enroll approximately 4674 patients in this NIS (2337 patients per arm). The patient population will include postmenopausal women with hormone-receptor positive primary breast cancer scheduled for upfront adjuvant endocrine treatment with anastrozole according to the current standard medical procedures.

Official title: A Randomised in Practice Evaluation of the Influence of Patient's Understanding of Her Disease and Therapy on Persistence and Compliance to Adjuvant Therapy for Post-Menopausal Hormone Sensitive Early Breast Cancer

Study design: Cohort, Prospective

Primary outcome: Compliance rate and persistence rate

Secondary outcome:

Time to treatment discontinuation

Demographics and other baseline characteristics as well as information regarding concomitant medication, quality of life

The percentage number of patients with disease free survival

Time of disease free survival

Minimum age: 18 Years. Maximum age: N/A. Gender(s): Female.

Criteria:

Inclusion Criteria:

- Histological/cytological confirmed primary diagnosis of early breast cancer

- Postmenopausal

- Hormone receptor positive

Exclusion Criteria:

- Patients with severe renal function disorders

- Patients with moderate or severe disorders of hepatic function

- Concomitant treatment with drugs known to affect sex hormonal status and tamoxifen

AstraZeneca Germany Clinical Study, Information, Phone: +49 4103-708-3814, Email: brigette.gutendorf@astrazeneca.com

Research Site, Alsdorf, Germany; Recruiting

Research Site, Amberg, Germany; Recruiting

Research Site, Andernach, Germany; Recruiting

Research Site, Augsburg, Germany; Recruiting

Research Site, Bad Breisig, Germany; Recruiting

Research Site, Bad Durkheim, Germany; Recruiting

Research Site, Bad Oldesloe, Germany; Recruiting

Research Site, Bad Reichenhall, Germany; Recruiting

Research Site, Bad Saarow, Germany; Recruiting

Research Site, Bad Tolz, Germany; Recruiting

Research Site, Bad Windsheim, Germany; Recruiting

Research Site, Bautzen, Germany; Recruiting

Research Site, Bayreuth, Germany; Recruiting

Research Site, Berlin, Germany; Recruiting

Research Site, Bielefeld, Germany; Recruiting

Research Site, Bobingen, Germany; Recruiting

Research Site, Bocholt, Germany; Recruiting

Research Site, Bochum, Germany; Recruiting

Research Site, Bonn, Germany; Recruiting

Research Site, Brandenburg, Germany; Recruiting

Research Site, Chemnitz, Germany; Recruiting

Research Site, Coesfeld, Germany; Recruiting

Research Site, Dachau, Germany; Recruiting

Research Site, Deggendorf, Germany; Recruiting

Research Site, Delitzsch, Germany; Recruiting

Research Site, Dernbach, Germany; Recruiting

Research Site, Dessau, Germany; Recruiting

Research Site, Dillingen, Germany; Recruiting

Research Site, Ditzingen, Germany; Recruiting

Research Site, Dortmund, Germany; Recruiting

Research Site, Dreieich, Germany; Recruiting

Research Site, Dresden, Germany; Recruiting

Research Site, Duisburg, Germany; Recruiting

Research Site, Dusseldorf, Germany; Recruiting

Research Site, Ebersberg, Germany; Recruiting

Research Site, Eggenfelden, Germany; Recruiting

Research Site, Ellwangen, Germany; Recruiting

Research Site, Emmendingen, Germany; Recruiting

Research Site, Erfurt, Germany; Recruiting

Research Site, Essen, Germany; Recruiting

Research Site, Flensburg, Germany; Recruiting

Research Site, Frankfurt, Germany; Recruiting

Research Site, Frankfurt am Main, Germany; Recruiting

Research Site, Freiburg, Germany; Recruiting

Research Site, Furstenwalde, Germany; Recruiting

Research Site, Furth, Germany; Recruiting

Research Site, Gelsenkirchen, Germany; Recruiting

Research Site, Gera, Germany; Recruiting

Research Site, Geretsried, Germany; Recruiting

Research Site, Gerlingen, Germany; Recruiting

Research Site, Gieben, Germany; Recruiting

Research Site, Gifhorn, Germany; Recruiting

Research Site, Graefelfing, Germany; Recruiting

Research Site, Grimmen, Germany; Recruiting

Research Site, Gummersbach, Germany; Recruiting

Research Site, Guenzburg, Germany; Recruiting

Research Site, Gusten, Germany; Recruiting

Research Site, Halle, Germany; Recruiting

Research Site, Hamburg, Germany; Recruiting

Research Site, Hamein, Germany; Recruiting

Research Site, Hannover, Germany; Recruiting

Research Site, Harzgerode, Germany; Recruiting

Research Site, Heide, Germany; Recruiting

Research Site, Heidenheim, Germany; Recruiting

Research Site, Heilbronn, Germany; Recruiting

Research Site, Herdecke, Germany; Recruiting

Research Site, Herne, Germany; Recruiting

Research Site, Hersbruck, Germany; Recruiting

Research Site, Hessisch Oldendorf, Germany; Recruiting

Research Site, Hildesheim, Germany; Recruiting

Research Site, Hof, Germany; Recruiting

Research Site, Homburg, Germany; Recruiting

Research Site, Itzehoe, Germany; Recruiting

Research Site, Jena, Germany; Recruiting

Research Site, Karlsruhe, Germany; Recruiting

Research Site, Kassel, Germany; Recruiting

Research Site, Kempten, Germany; Recruiting

Research Site, Kiel, Germany; Recruiting

Research Site, Koblenz, Germany; Recruiting

Research Site, Koln, Germany; Recruiting

Research Site, Konigs Wusterhausen, Germany; Recruiting

Research Site, Konstanz, Germany; Recruiting

Research Site, Krombach, Germany; Recruiting

Research Site, Lahnstein, Germany; Recruiting

Research Site, Landshut, Germany; Recruiting

Research Site, Lehrte, Germany; Recruiting

Research Site, Leipzig, Germany; Recruiting

Research Site, Lohsa ot Weibkollm, Germany; Recruiting

Research Site, Lubeck, Germany; Recruiting

Research Site, Ludwigsfelde, Germany; Recruiting

Research Site, Lunen, Germany; Recruiting

Research Site, Magdeburg, Germany; Recruiting

Research Site, Marktoberdorf, Germany; Recruiting

Research Site, Marktredwitz, Germany; Recruiting

Research Site, Marl, Germany; Recruiting

Research Site, Mayen, Germany; Recruiting

Research Site, Memmingen, Germany; Recruiting

Research Site, Metzingen, Germany; Recruiting

Research Site, Moers, Germany; Recruiting

Research Site, Mossingen, Germany; Recruiting

Research Site, Muhlhausen, Germany; Recruiting

Research Site, Muelheim, Germany; Recruiting

Research Site, Munchen, Germany; Recruiting

Research Site, Munster, Germany; Recruiting

Research Site, Neusab, Germany; Recruiting

Research Site, Neustadt, Germany; Recruiting

Research Site, Oberhausen, Germany; Recruiting

Research Site, Oberstdorf, Germany; Recruiting

Research Site, Ochsenfurt, Germany; Recruiting

Research Site, Offenbach, Germany; Recruiting

Research Site, Osnabruck, Germany; Recruiting

Research Site, Paderborn, Germany; Recruiting

Research Site, Preetz, Germany; Recruiting

Research Site, Prien, Germany; Recruiting

Research Site, Revensburg, Germany; Recruiting

Research Site, Recklinghausen, Germany; Recruiting

Research Site, Regensburg, Germany; Recruiting

Research Site, Rendsburg, Germany; Recruiting

Research Site, Reutlingen, Germany; Recruiting

Research Site, Rheinfelden, Germany; Recruiting

Research Site, Rosenheim, Germany; Recruiting

Research Site, Rosrath, Germany; Recruiting

Research Site, Rottweil, Germany; Recruiting

Research Site, Schkeuditz, Germany; Recruiting

Research Site, Schwalbach, Germany; Recruiting

Research Site, Schwabisch Gmund, Germany; Recruiting

Research Site, Schwandorf, Germany; Recruiting

Research Site, Sebnitz, Germany; Recruiting

Research Site, Sigmaringen, Germany; Recruiting

Research Site, Sommerda, Germany; Recruiting

Research Site, Spremberg, Germany; Recruiting

Research Site, Sprockhovel, Germany; Recruiting

Research Site, St. Wendel, Germany; Recruiting

Research Site, Stralsund, Germany; Recruiting

Research Site, Stuttgart, Germany; Recruiting

Research Site, Torgau, Germany; Recruiting

Research Site, Traunstein, Germany; Recruiting

Research Site, Tubingen, Germany; Recruiting

Research Site, Ulm, Germany; Recruiting

Research Site, Villingen-Schwenningen, Germany; Recruiting

Research Site, Waldmuenchen, Germany; Recruiting

Research Site, Weiden in der Oberpfalz, Germany; Recruiting

Research Site, Wiesbaden, Germany; Recruiting

Research Site, Wilhelmshaven, Germany; Recruiting

Research Site, Wilster, Germany; Recruiting

Research Site, Witten, Germany; Recruiting

Research Site, Wolfen, Germany; Recruiting

Research Site, Worms, Germany; Recruiting

Research Site, Wunstorf, Germany; Recruiting

Research Site, Wurzburg, Germany; Recruiting

Starting date: October 2006
Ending date: June 2014
Last updated: July 1, 2008