Chronic Obstructive Pulmonary Disease (COPD) Patients Diagnosed With Gastro Esophageal Reflux Disease (GERD). Rates of COPD Exacerbations After Treatment With High Dose Proton Pump Inhibitor Therapy
Information source: University of Florida
Information obtained from ClinicalTrials.gov on November 03, 2008
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Gastroesophageal Reflux; Chronic Obstructive Pulmonary Disease
Phase: N/A
Status: Recruiting
Sponsored by: University of Florida Official(s) and/or principal investigator(s):
Kenneth Vega, MD, Principal Investigator, Affiliation: University of Florida - Jacksonville
Overall contact:
Kenneth Vega, MD, Phone: 904-633-0089, Email: kenneth.vega@jax.ufl.edu
Summary
The purpose of this study is to determine which COPD patients have GERD and if COPD patients
with GERD treated with high dose lansoprazole for 1 year decreases the frequency of COPD
exacerbations compared to the previous year without treatment.
Clinical Details
Official title: COPD Patients Diagnosed With Gastro Esophageal Reflux Disease Have Decreased Rates of COPD Exacerbations After Treatment With High Dose Proton Pump Inhibitor Therapy (Esomeprazole or Lansoprazole)
Study design: Other, Prospective
Eligibility
Minimum age: 40 Years.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- diagnosis of COPD
- forced expiratory volume/forced vital capacity ratio (FEV1/FVC) of < 70% on
pulmonary function testing
- age > 40 years
- >20 pack year history of smoking
Exclusion Criteria:
- presence of the following disorders: respiratory disorders other than COPD, known
esophageal disease such as cancer, achalasia, stricture, active peptic ulcer disease,
Zollinger-Ellison syndrome, mastocytosis, scleroderma, or current abuse of alcohol
defined as greater than three alcoholic drinks per day.
Locations and Contacts
Kenneth Vega, MD, Phone: 904-633-0089, Email: kenneth.vega@jax.ufl.edu
University of Florida, Jacksonville, Florida 32207, United States; Recruiting
Kenneth Vega, MD, Phone: 904-633-0089, Email: kenneth.vega@jax.ufl.edu
Lakina Campbell, MS, CCRP, Phone: 904-633-0089, Email: lakina.campbell@jax.ufl.edu
Kenneth Vega, MD, Principal Investigator
Additional Information
Starting date: August 2007
Last updated: June 23, 2008
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