Dietary Vitamin A Requirement in Chinese Children and the New Technology of Dietary Assessment
Information source: Huazhong University of Science and Technology
ClinicalTrials.gov processed this data on August 20, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Vitamin A Deficiency
Phase: N/A
Status: Completed
Sponsored by: Huazhong University of Science and Technology Official(s) and/or principal investigator(s): Xiufa Sun, BS, Principal Investigator, Affiliation: Tongji Medical College, Huazhong University of Science and Technology
Summary
Vitamin A deficiency remains a major public health problem in developing country worldwide.
Young Children are considered to be at greatest risk of deficiency. However, there is little
information on the vitamin A requirement of Chinese children. In the present study, about
400 children aged between 4 and 9 years old in a kindergarten and an elementary school of
Shiyan City were screened before admission by questionnaire and anthropometric measurement.
The vitamin A status of children was assessed by serum vitamin A level, relative dosage
reaction and stable-isotope dilution technique. At the same time, their dietary vitamin A
intakes were estimated by weighted-food dietary survey. The dietary vitamin A requirement in
young children was determined on the basis of dietary vitamin A intakes in Children with
adequate vitamin A level.
Clinical Details
Official title: Estimating Dietary Vitamin A Requirement in Chinese Children by Stable-isotope Dilution Technique
Study design: Time Perspective: Cross-Sectional
Eligibility
Minimum age: 4 Years.
Maximum age: 9 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- well-nourished children with normal serum retinol(>=1. 40umol/L)
Exclusion Criteria:
- ongoing or previous illnesses,
- having taken nutritional supplements within 3 months,
- positive results in the fat absorption test or parasite test,
- increased level of CRP (> 8 mg/L), or
- lower serum level of retinol (< 1. 40 umol/L)
Locations and Contacts
Shiyan Centre for Disease Control and Prevention, Shiyan, Hubei 442500, China
Additional Information
Starting date: July 2009
Last updated: March 20, 2012
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