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Dietary Vitamin A Requirement in Chinese Children and the New Technology of Dietary Assessment

Information source: Huazhong University of Science and Technology
ClinicalTrials.gov processed this data on August 20, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Vitamin A Deficiency

Phase: N/A

Status: Completed

Sponsored by: Huazhong University of Science and Technology

Official(s) and/or principal investigator(s):
Xiufa Sun, BS, Principal Investigator, Affiliation: Tongji Medical College, Huazhong University of Science and Technology

Summary

Vitamin A deficiency remains a major public health problem in developing country worldwide. Young Children are considered to be at greatest risk of deficiency. However, there is little information on the vitamin A requirement of Chinese children. In the present study, about 400 children aged between 4 and 9 years old in a kindergarten and an elementary school of Shiyan City were screened before admission by questionnaire and anthropometric measurement. The vitamin A status of children was assessed by serum vitamin A level, relative dosage reaction and stable-isotope dilution technique. At the same time, their dietary vitamin A intakes were estimated by weighted-food dietary survey. The dietary vitamin A requirement in young children was determined on the basis of dietary vitamin A intakes in Children with adequate vitamin A level.

Clinical Details

Official title: Estimating Dietary Vitamin A Requirement in Chinese Children by Stable-isotope Dilution Technique

Study design: Time Perspective: Cross-Sectional

Eligibility

Minimum age: 4 Years. Maximum age: 9 Years. Gender(s): Both.

Criteria:

Inclusion Criteria:

- well-nourished children with normal serum retinol(>=1. 40umol/L)

Exclusion Criteria:

- ongoing or previous illnesses,

- having taken nutritional supplements within 3 months,

- positive results in the fat absorption test or parasite test,

- increased level of CRP (> 8 mg/L), or

- lower serum level of retinol (< 1. 40 umol/L)

Locations and Contacts

Shiyan Centre for Disease Control and Prevention, Shiyan, Hubei 442500, China
Additional Information

Starting date: July 2009
Last updated: March 20, 2012

Page last updated: August 20, 2015

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