High Dose and Low Dose of Atorvastatin in Patients With Unstable Angina and NSTEMI (Non ST Elevation MI)
Information source: Hormozgan University of Medical Sciences
ClinicalTrials.gov processed this data on August 23, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Cardiovascular Disease
Intervention: Low dose Atorvastatin (Drug); High dose atorvastatin (Drug)
Phase: N/A
Status: Completed
Sponsored by: Hormozgan University of Medical Sciences Official(s) and/or principal investigator(s): Vahid Vahdatkhah, Principal Investigator, Affiliation: Hormozgan University of Medical Sciences
Summary
The aim of this study is to compare the effect of high dose and low dose of Atorvastatin in
reduction level of C-reactive protein (CRP) in patients with unstable angina and NSTEMI (Non
ST Elevation MI) attending Shahid Mohammadi hospital in Bandar Abbas.
Clinical Details
Official title: Comparison Between Effect of High Dose and Low Dose of Atorvastatin in Reduction Level of CRP in Patients With Unstable Angina and NSTEMI (Non ST Elevation MI)
Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment
Primary outcome: CRP reduction
Secondary outcome: Drug side effects
Detailed description:
This study compare the effect of 80mg atorvastatin followed by two 20mg daily atorvastatin
with three 80mg daily atorvastatin in reduction of CRP in patients with unstable angina and
NSTEMI (Non ST Elevation MI) attending Shahid Mohammadi hospital in Bandar Abbas in 2009.
Eligibility
Minimum age: N/A.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Patients with unstable angina with chest discomfort at rest with normal EKG or St
depression (at least 0. 1mv) in two consecutive leads or new and deep T inversion (at
least 0. 2mv)
Exclusion Criteria:
- Myocardial Infarction with ST elevation
- Diabetes Mellitus
- Previous statin use
- Current infectious disease
Locations and Contacts
Hormozgan University of Medical Sciences, Bandar Abbas, Hormozgan 097145-3388, Iran, Islamic Republic of
Additional Information
Starting date: January 2009
Last updated: March 1, 2011
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