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High Dose and Low Dose of Atorvastatin in Patients With Unstable Angina and NSTEMI (Non ST Elevation MI)

Information source: Hormozgan University of Medical Sciences
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Cardiovascular Disease

Intervention: Low dose Atorvastatin (Drug); High dose atorvastatin (Drug)

Phase: N/A

Status: Completed

Sponsored by: Hormozgan University of Medical Sciences

Official(s) and/or principal investigator(s):
Vahid Vahdatkhah, Principal Investigator, Affiliation: Hormozgan University of Medical Sciences

Summary

The aim of this study is to compare the effect of high dose and low dose of Atorvastatin in reduction level of C-reactive protein (CRP) in patients with unstable angina and NSTEMI (Non ST Elevation MI) attending Shahid Mohammadi hospital in Bandar Abbas.

Clinical Details

Official title: Comparison Between Effect of High Dose and Low Dose of Atorvastatin in Reduction Level of CRP in Patients With Unstable Angina and NSTEMI (Non ST Elevation MI)

Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Primary outcome: CRP reduction

Secondary outcome: Drug side effects

Detailed description: This study compare the effect of 80mg atorvastatin followed by two 20mg daily atorvastatin with three 80mg daily atorvastatin in reduction of CRP in patients with unstable angina and NSTEMI (Non ST Elevation MI) attending Shahid Mohammadi hospital in Bandar Abbas in 2009.

Eligibility

Minimum age: N/A. Maximum age: N/A. Gender(s): Both.

Criteria:

Inclusion Criteria:

- Patients with unstable angina with chest discomfort at rest with normal EKG or St

depression (at least 0. 1mv) in two consecutive leads or new and deep T inversion (at least 0. 2mv) Exclusion Criteria:

- Myocardial Infarction with ST elevation

- Diabetes Mellitus

- Previous statin use

- Current infectious disease

Locations and Contacts

Hormozgan University of Medical Sciences, Bandar Abbas, Hormozgan 097145-3388, Iran, Islamic Republic of
Additional Information

Starting date: January 2009
Last updated: March 1, 2011

Page last updated: August 23, 2015

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