Intraocular Pressure, Blood Pressure, Ocular Perfusion and Blood Flow Fluctuations in Glaucoma Patients
Information source: Lithuanian University of Health Sciences
Information obtained from ClinicalTrials.gov on December 08, 2011
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Open Angle Glaucoma
Intervention: Color Doppler Imaging (Device)
Phase: N/A
Status: Recruiting
Sponsored by: Lithuanian University of Health Sciences Official(s) and/or principal investigator(s):
Ingrida Januleviciene, MD, Principal Investigator, Affiliation: Lithuania University of Health Science
Overall contact:
Ingrida Januleviciene, MD, Phone: +37068655792, Email: ingrida.januleviciene@kaunoklinikos.lt
Summary
To evaluate whether add-on to prostaglandin therapy with twice a day (bid) dorzolamide is
statistically superior to twice a day (bid) timolol with regard to increasing ocular blood
flow
Clinical Details
Official title: Comparison of Intraocular Pressure, Blood Pressure, Ocular Perfusion and Blood Flow Fluctuations During the Addition of Dorzolamid vs Timolol in Glaucoma Subjects Treated With Prostaglandin Analogue Monotherapy
Study design: Observational Model: Case-Crossover, Time Perspective: Prospective
Primary outcome: Ocular Color Doppler Imaging
Secondary outcome: IOP, BP, OPP (mean, fluctuations, amplitude)
Detailed description:
Hypotensive treatments for glaucomatous optic neuropathy (GON), depending on their chemical
composition can influence the ocular circulation independent of intraocular pressure (IOP)
reduction. It is therefore important not only to identify ocular blood flow deficits in
GON, but also document the influence of GON treatments on the ocular circulation
Eligibility
Minimum age: 18 Years.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Open angle glaucoma subjects receiving prostaglandin monotherapy in both eyes
Exclusion Criteria:
- younger than 18 years old
- women of child bearing potential
Locations and Contacts
Ingrida Januleviciene, MD, Phone: +37068655792, Email: ingrida.januleviciene@kaunoklinikos.lt
Eye Clinic Lithuania Health Science Hospital Kaunas Clinics, Kaunas 50009, Lithuania; Recruiting
Ingrida Januleviciene, MD, Email: ingrida.januleviciene@kaunoklinikos.lt
Additional Information
Starting date: March 2011
Last updated: March 10, 2011
|
