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Intraocular Steroid After Cataract Surgery Study

Information source: Dean Health System
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Cataract

Intervention: intraocular triamcinolone and gatifloxicin (Drug)

Phase: N/A

Status: Completed

Sponsored by: Dean Health System

Official(s) and/or principal investigator(s):
Jonathan G Stock, MD, Principal Investigator, Affiliation: Dean Health Systems


The use of one dose of an antibiotic and steroid injected into the eye at the end of cataract surgery is as safe and effective as the post operative use of eyedrops after cataract surgery.

Clinical Details

Official title: Intracameral Use of Triamcinolone and Gatifloxacin Versus Standard Postoperative Steroid and Antibiotic Eye Drops After Cataract Surgery

Study design: Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Primary outcome: visual acuity

Secondary outcome: intraocular inflammation

Detailed description: This prospective randomized controlled trial included 80 eyes of 40 patients having routine phacoemulsification of cataract. Patients between 40 and 80 years of age who met enrollment criteria, required cataract surgery in both eyes, and agreed to participate, were enrolled in the study over a nine month period in 2006 at the office of one cataract surgeon. Eyes were randomly assigned to receive either the eye drop or injection protocol on the initial consultative visit. All surgery was preformed by one surgeon (JGS) using topical anesthesia, the Infiniti phacoemulsification system (Alcon) and an Acrysof SN60WF (Alcon) intraocular lens. The fellow eye was operated upon using the same technique and instrumentation two weeks later and was assigned to the group opposite the first eye. All eyes were examined by the operating surgeon at days 1, 8, 15, 30 and 90 postoperatively with uncorrected visual acuity, best corrected visual acuity, intraocular pressure, corneal edema, anterior chamber cell and flare recorded.


Minimum age: 40 Years. Maximum age: 80 Years. Gender(s): Both.


Inclusion Criteria:

- Inclusion criteria for patients to enter the study included age 40 to 80 years,

clinically significant cataract in both eyes, the patient’s willingness to enter the study and have cataract surgery preformed on each eye in a sequentially within a two or three week time frame. Exclusion Criteria:

- Exclusion criteria included a history of glaucoma, retinopathy of any type,

pseudoexfoliation, other significant ocular co morbidity and systemic diabetes.

Locations and Contacts

Davis Duehr Dean Baraboo, Baraboo, Wisconsin 53913, United States
Additional Information

Related publications:

Gills JP, Gills P. Effect of intracameral triamcinolone to control inflammation following cataract surgery. J Cataract Refract Surg. 2005 Aug;31(8):1670-1.

Starting date: March 2006
Last updated: May 24, 2007

Page last updated: August 23, 2015

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