A Comparative Study of the Safety and Efficacy of Face Talc Slurry and Iodopovidone for Pleurodesis
Information source: Postgraduate Institute of Medical Education and Research
Information obtained from ClinicalTrials.gov on November 03, 2008
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Malignant Pleural Effusions; Recurrent Pleural Effusions; Primary Spontaneous Pneumothorax; Secondary Spontaneous Pneumothorax
Intervention: Pleurodesis with either talc or iodopovidone (Procedure)
Phase: N/A
Status: Recruiting
Sponsored by: Postgraduate Institute of Medical Education and Research Official(s) and/or principal investigator(s):
Dheeraj Gupta, MD, DM, FCCP, Principal Investigator, Affiliation: Additional Professor, Dept of Pulmonary Medicine, PGIMER, Chandigarh, India
Summary
Pleurodesis is a technique used to fuse the two layers of the lining over the lung. This is
done to get rid of collections of fluid or air in this space. A common reason would be
cancer of the underlying lung or elsewhere causing fluid to collect in the pleural space. In
this situation it is a palliative procedure to free the patient from symptoms like
breathlessness.
Clinical Details
Official title: A Comparative Study of the Safety and Efficacy of Face Talc Slurry and Iodopovidone for Pleurodesis
Study design: Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Safety/Efficacy Study
Primary outcome: SuccessFailure
Secondary outcome: DeathPain by VAS Time to Pleurodesis Others
Detailed description:
Pleurodesis is a technique used to fuse the two layers of the pleura. This is done to
prevent reaccumulation of collections of fluid or air in this space. Common indications are
malignant pleural effusions, recurrent pneumothorax and even benign effusions which are
otherwise difficult to eradicate.
Eligibility
Minimum age: 12 Years.
Maximum age: N/A.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Age over 12 years
- Symptomatic recurrent pleural effusion
- Pneumothorax needing pleurodesis
Exclusion Criteria:
- Life expectancy <1 month
- Unwilling to give consent
- Empyema
- ICTD drain output >150 ml/d
- Presence of an airleak
Locations and Contacts
PGIMER, Chandigarh 160 012, India; Recruiting
Abinash Paul, MD, Phone: 91-9417745955, Email: draspaul@yahoo.co.in
Ritesh Agarwal, MD DM, Phone: 91- 9815799226, Email: ritesh@indiachest.org
Additional Information
Starting date: January 2006
Ending date: December 2007
Last updated: February 1, 2007
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