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Two Different Preparations of Sevoflurane in Induction

Information source: Istanbul University
ClinicalTrials.gov processed this data on August 23, 2015
Link to the current ClinicalTrials.gov record.

Condition(s) targeted: Coughing on Induction; Vapors; Inhalation

Intervention: Sevoflurane (Drug); Sevoflurane (Drug)

Phase: Phase 4

Status: Completed

Sponsored by: Istanbul University


In our study we aim to study the effects of two preparations of Sevoflurane in vital capacity rapid inhalation induction.

Clinical Details

Official title: A Randomized Clinical Trial on the Efficiency, Hemodynamic Effects and Patient Comfort of Two Different Preparations of Sevoflurane After Vital Capacity Rapid Inhalation Induction

Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Primary outcome: effect of different preparations of sevoflurane on Induction on hypnosis time

Secondary outcome: effect of different sevoflurane preparations on hemodynamics


Minimum age: 18 Years. Maximum age: 80 Years. Gender(s): Both.


Inclusion Criteria:

- Patients undergoing abdominal surgery

Exclusion Criteria:

- Patients with any cardiovascular or respiratory disease, usage of any kind of

sedative drug, expected airway difficulty and obese patients (BMI>35) will be excluded from the study

Locations and Contacts

Cerrahpasa Medical Faculty Anesthesiology and Reanimation Department, Istanbul, Fatih 34400, Turkey
Additional Information

Related publications:

Baker MT. Sevoflurane: are there differences in products? Anesth Analg. 2007 Jun;104(6):1447-51, table of contents. Review.

Starting date: February 2013
Last updated: April 18, 2013

Page last updated: August 23, 2015

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