Heredity of Retinal Vessel Tortuosity
Information source: Glostrup University Hospital,Copenhagen
Information obtained from ClinicalTrials.gov on May 04, 2007
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Retinopathy of Prematurity
Status: Completed
Sponsored by: Glostrup University Hospital,Copenhagen Official(s) and/or principal investigator(s):
Michael Larsen, Prof. MD, Principal Investigator, Affiliation: Department of Ophthalmology Glostrup Hospital University of Copenhagen
Summary
The purpose of this study is to asses the relative influence of genetic and environmental influence on the tortuosity of retinal arterioles in eyes of 218 healthy Danish twins aged 20-46 years. We expect to find a high heredity for the variation in tortuosity. This knowledge can contribute to the elucidation of the pathology in retinal diseases.
Clinical Details
Official title:
Heredity of Retinal Vessel Tortuosity - A Twin Study
Study design: Observational, Natural History, Cross-Sectional, Defined Population, Prospective Study
Detailed description:
All persons underwent an ophthalmic examination including refraction, slit lamp biomicroscopy and digital fundus photography. Two independent graders (both with an MD degree) made a visual grading of the severity of tortuosity of the retinal arterioles in the fundus images.
Eligibility
Minimum age: 20 Years.
Maximum age: 46 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Samesex twin pairs of self-assessed good health
Exclusion Criteria:
- Diabetes mellitus
- Hypertension
- Thyroid disease
- Cataract or other opacities of the refractive media
- Missing fundus photographs
Locations and Contacts
Department of Ophthalmology Glostrup Hospital, Glostrup, Copenhagen County DK-2600, Denmark
Additional Information
Starting date:
January 1998
Ending date: December 1998
Last updated: January 25, 2007
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