Bone Disease in Severely Burned Children
Information source: The University of Texas, Galveston
Information obtained from ClinicalTrials.gov on November 03, 2008
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Burn
Intervention: Tetracycline (Drug); DEXA (Radiation); Bone Biopsy (Procedure)
Phase: Phase 2/Phase 3
Status: Recruiting
Sponsored by: The University of Texas, Galveston Official(s) and/or principal investigator(s):
Klein Gordon, M.D., Principal Investigator, Affiliation: U.T.M.B.
Overall contact:
Gordon Klein, M.D., Phone: 409-772-1689, Email: gklein@utmb.edu
Summary
Bone metabolism is adversely affected by severe burns in children for a period of time.
Clinical Details
Official title: Bone Disease in Severely Burned Children
Study design: Treatment, Open Label, Active Control, Single Group Assignment, Safety/Efficacy Study
Primary outcome: Determine Bone Health(bone growth,strength,and content) in burn injured patients.
Detailed description:
More closely monitored biochemical and radiologic parameters of bone and mineral metabolism
will increase the likelihood of earlier detection of abnomalities and possible therapeutic
interventions.
Eligibility
Minimum age: 5 Years.
Maximum age: 18 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Children age 5-18 years old with at least 40% or more of their body burned.
Exclusion Criteria:
- Anyone with a burn covering less than 40% of the body or whose burn covers the front
of both hipbones.
- Anyone younger than 5 years old, anyone with a history of cancer or other metabolic
disease process, or anyone who is pregnant or has an allergy to Tetracycline will also
be excluded.
- Anyone who has participated in an investigational drug trial within the past 60 days
from date of admission will be excluded from this study.
Locations and Contacts
Gordon Klein, M.D., Phone: 409-772-1689, Email: gklein@utmb.edu
U.T.M.B., Galveston, Texas 77550, United States; Recruiting
Deb Benjamin, R.N.M.S.N., Phone: 409-770-6740, Email: dbenjami@utmb.edu
Carroll Miller, Phone: 409-770-6728, Email: cmiller@utmb.edu
Klein Gordon, M.D., Principal Investigator
Additional Information
Starting date: October 1992
Ending date: October 2011
Last updated: June 25, 2008
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