Antabuse in Severe Alcoholism: an Open Controlled Study
Information source: Psykiatrisk Center Gentofte
Information obtained from ClinicalTrials.gov on February 07, 2013
Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Alcoholism
Intervention: antabuse (disulfiram) (Drug)
Phase: Phase 4
Status: Recruiting
Sponsored by: Psykiatrisk Center Gentofte Official(s) and/or principal investigator(s):
Jakob Ulrichsen, MD, ph.d., Principal Investigator, Affiliation: Psykiatrisk Center Gentofte
Summary
Newly detoxified alcoholics (N=60) are randomised to either antabuse (disulfiram) treatment
or the control group for a total of 6 months. All patients will receive cognitive behavioural
treatment in groups. The hypothesis to be tested is that more of the patients who receive
antabuse (disulfiram) will be alcohol free during the 6 months treatment period compared to
the control group. The trial is open.
Clinical Details
Official title: Antabuse in Severe Alcoholism: an Open Controlled Study
Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Primary outcome: The number of patients in each group who have not been drinking alcohol after 6 months of treatment.
Eligibility
Minimum age: 18 Years.
Maximum age: 70 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- Alcoholism
- Living in the departments catchment area
Exclusion Criteria:
- Pregnancy
- Schizophrenia
- Bipolar disorder
- Other substance abuse
- Dementia
- Anorexia
Locations and Contacts
Psykiatrisk Center Gentofte, Hellerup 2900, Denmark; Recruiting
Jakob Ulrichsen, MD, ph.d., Phone: (45) 3977 3650, Email: jaul@geh.regionh.dk
Jakob Ulrichsen, MD, ph.d., Principal Investigator
Additional Information
Starting date: February 2007
Last updated: March 2, 2007
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