Study Evaluating Etanercept and Sulphasalazine in Ankylosing Spondylitis

Condition(s) targeted: Ankylosing Spondylitis

Intervention: etanercept (Drug); sulphasalazine (Drug)

Phase: Phase 4

Status: Recruiting

Sponsored by: Wyeth

Official(s) and/or principal investigator(s):
Medical Monitor, Study Director, Affiliation: Wyeth
Trial Manager, Principal Investigator, Affiliation: For Poland, WPWZMED@wyeth.com
Trial Manager, Principal Investigator, Affiliation: For Italy, descresg@wyeth.com
Trial Manager, Principal Investigator, Affiliation: For Hungary, WPBUMED@wyeth.com
Trial Manager, Principal Investigator, Affiliation: For Czech Republic, WPPGCLI@wyeth.com
Trial Manager, Principal Investigator, Affiliation: For Australia, medinfo@wyeth.com
Trial Manager, Principal Investigator, Affiliation: For Germany, medinfoDEU@wyeth.com
Trial Manager, Principal Investigator, Affiliation: For Austria, WPVIMED@wyeth.com
Trial Manager, Principal Investigator, Affiliation: For Spain, infomed@wyeth.com
Trial Manager, Principal Investigator, Affiliation: For Netherlands, trials-NL@wyeth.com
Trial Manager, Principal Investigator, Affiliation: For Denmark, medinfonord@wyeth.com
Trial Manager, Principal Investigator, Affiliation: For Finland, MedInfoNord@wyeth.com
Trial Manager, Principal Investigator, Affiliation: For Sweden, MedInfoNord@wyeth.com
Trial Manager, Principal Investigator, Affiliation: For UK/Great Britian, ukmedinfo@wyeth.com
Trial Manager, Principal Investigator, Affiliation: For Ireland, ukmedinfo@wyeth.com
Trial Manager, Principal Investigator, Affiliation: For France, infomedfrance@wyeth.com
Trial Manager, Principal Investigator, Affiliation: For China, medinfo@wyeth.com

Overall contact:
Trial Manager, Email: clintrialparticipation@wyeth.com

The purpose of this study is to compare the efficacy of etanercept and sulphasalazine in the treatment of Ankylosing Spondylitis.

Official title: A Randomized, Double-Blind Study Evaluating the Safety and Efficacy of Etanercept and Sulphasalazine in Subjects With Ankylosing Spondylitis

Study design: Treatment, Randomized, Double Blind (Subject, Investigator), Active Control, Parallel Assignment, Efficacy Study

Primary outcome: To compare the efficacy of etanercept with sulphasalazine in the treatment of ankylosing spondylitis.

Secondary outcome: To compare the effect of etanercept with sulphasalazine on the quality of life. To evaluate the safety of etanercept.

Minimum age: 18 Years. Maximum age: N/A. Gender(s): Both.

Criteria:

Inclusion Criteria:

- Clinical diagnosis of ankylosing spondylitis

- Active ankylosing spondylitis

Exclusion Criteria:

- Complete ankylosis of spine

- Previous treatment with etanercept

Trial Manager, Email: clintrialparticipation@wyeth.com

Innsbruck 6020, Austria; Terminated

Linz A-4020, Austria; Recruiting

Klagenfurt A-9020, Austria; Recruiting

Beijing 100853, China; Recruiting

Shanghai 200001, China; Recruiting

Praha 120 00, Czech Republic; Recruiting

Ostrava 722 00, Czech Republic; Recruiting

Frederiksberg DK-2000, Denmark; Recruiting

Vejle 7100, Denmark; Recruiting

Odense 5000, Denmark; Recruiting

Kolding 6000, Denmark; Not yet recruiting

Helsinki 00029, Finland; Recruiting

Kuopio 70211, Finland; Recruiting

Tampere 33100, Finland; Recruiting

Orleans 45032, France; Recruiting

Creteil 94010, France; Not yet recruiting

Amiens 80054, France; Recruiting

Toulouse 31059, France; Terminated

Marseille 13005, France; Not yet recruiting

Bordeaux 33076, France; Recruiting

Pierre Mendès 76290, France; Terminated

Boulogne Billancourt 92104, France; Recruiting

Nantes 44000, France; Terminated

Herne D-44652, Germany; Recruiting

Ratingen D-40882, Germany; Recruiting

Wiesbaden D-65191, Germany; Active, not recruiting

Berlin 12200, Germany; Recruiting

Erlangen D-91054, Germany; Recruiting

Hamburg D-22081, Germany; Recruiting

Hildesheim D-31134, Germany; Recruiting

Heubnerweg D-14059, Germany; Recruiting

Muenchen D-80639, Germany; Active, not recruiting

Pirna D-01796, Germany; Recruiting

Berlin D-10117, Germany; Recruiting

Gommern D-39245, Germany; Recruiting

Wiesbaden 65185, Germany; Recruiting

Gyor 9025, Hungary; Recruiting

Pecs 7621, Hungary; Recruiting

Szeged 6724, Hungary; Terminated

Nyiregyhaza 4400, Hungary; Recruiting

Debrecen 4043, Hungary; Recruiting

Dublin, Ireland; Recruiting

Prato 59100, Italy; Recruiting

Benevento 82037, Italy; Recruiting

Roma 00161, Italy; Recruiting

Bergamo 24128, Italy; Recruiting

Monserrato 09042, Italy; Not yet recruiting

Potenza 85100, Italy; Not yet recruiting

Reggio Emilia 42100, Italy; Recruiting

Firenze 50143, Italy; Not yet recruiting

Roma 00189, Italy; Recruiting

Amsterdam 1081 HV, Netherlands; Recruiting

Maastricht 6229HX, Netherlands; Not yet recruiting

Nijmegen 6522JV, Netherlands; Recruiting

Groningen 9713GZ, Netherlands; Not yet recruiting

Leeuwarden 8934AD, Netherlands; Recruiting

Ustron Zawodzie 43-450, Poland; Recruiting

Warszawa 02-637, Poland; Recruiting

Wroclaw 53-137, Poland; Active, not recruiting

Lodz 93-513, Poland; Recruiting

Doha 3050, Qatar; Recruiting

Riyadh 11426, Saudi Arabia; Not yet recruiting

Tenerife 38010, Spain; Recruiting

Asturias 33012, Spain; Recruiting

Cordoba 14004, Spain; Recruiting

Barcelona 08003, Spain; Recruiting

Madrid 28035, Spain; Recruiting

Madrid 28922, Spain; Recruiting

Porto 4200-319, Spain; Recruiting

Solna 17176, Sweden; Recruiting

Ostra kyrkogardsgatan 59333, Sweden; Recruiting

Newcastle Upon Tyne NE7 7DN, United Kingdom; Recruiting

Cambridge CB2 2QQ, United Kingdom; Recruiting

Upper Borough Walls BA1 1RL, United Kingdom; Recruiting

Cannock WS11 2XY, United Kingdom; Recruiting

Liverpool L9 7AL, United Kingdom; Recruiting

Basingstoke RG24 9NA, United Kingdom; Recruiting

Glasgow G31 2ER, United Kingdom; Terminated

Granollers, Barcelona 08400, Spain; Recruiting

Wilton, Cork, Ireland; Not yet recruiting

Heidelberg West, Victoria 3081, Australia; Recruiting

Shenton Park, Western Australia 6000, Australia; Recruiting

Upton, Wirral L49 5PE, United Kingdom; Recruiting

Starting date: December 2005
Ending date: December 2007
Last updated: December 21, 2007