A Comparison of Morphine and Morphine Plus Dexmedetomidine in Chronic Cancer Pain
Information source: Cukurova University
ClinicalTrials.gov processed this data on August 23, 2015 Link to the current ClinicalTrials.gov record.
Condition(s) targeted: Chronic Pain
Intervention: Morphine (Drug); Morphine plus dexmedetomidine (Drug)
Phase: Phase 4
Status: Recruiting
Sponsored by: Cukurova University Official(s) and/or principal investigator(s): Selcuk Gök, M.D, Principal Investigator, Affiliation: Cukurova University
Overall contact: Ersel Gulec, M.D, Phone: +903223386060, Ext: 3262, Email: gulecersel@yahoo.com
Summary
The purpose of this study is to determine whether dexmedetomidine added to morphine is
effective in the treatment of chronic cancer pain.
Clinical Details
Official title: A Comparison of Morphine and Morphine Plus Dexmedetomidine in Chronic Cancer Pain
Study design: Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
Primary outcome: Morphine consumption (mg)
Secondary outcome: Pain score
Detailed description:
We conduct the study in Cukurova University Faculty of Medicine Research Hospital after
obtaining ethics committee approval and patient's informed consent. Patients with cancer
pain are allocated into two group to receive Patient Controlled Analgesia with morphine or
morphine plus dexmedetomidine.
Eligibility
Minimum age: 20 Years.
Maximum age: 80 Years.
Gender(s): Both.
Criteria:
Inclusion Criteria:
- patients with chronic cancer pain
- between 20-80 years old age
Exclusion Criteria:
- the presence of severe systemic disease(cardiac, pulmonary, hepatic or renal)
- psychiatric or neurologic disease
- unable to communicate verbally
- nausea and vomiting
- patient's refusal
Locations and Contacts
Ersel Gulec, M.D, Phone: +903223386060, Ext: 3262, Email: gulecersel@yahoo.com
Cukurova University Faculty of Medicine Research Hospital, Adana 01130, Turkey; Recruiting Ersel Gulec, M.D., Phone: +903223386060, Ext: 3289, Email: gulecersel@yahoo.com Selçuk Gök, M.D., Principal Investigator Ersel Gulec, M.D., Sub-Investigator Hayri Özbek, M.D., Sub-Investigator
Additional Information
Related publications: Blaudszun G, Lysakowski C, Elia N, Tramèr MR. Effect of perioperative systemic α2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials. Anesthesiology. 2012 Jun;116(6):1312-22. doi: 10.1097/ALN.0b013e31825681cb. Review.
Starting date: November 2014
Last updated: November 10, 2014
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